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首页> 外文期刊>Advances in Sexual Medicine >Aphrodisiac Activity of Aqueous Extract of Phoenix dactylifera Pollen in Male Rats
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Aphrodisiac Activity of Aqueous Extract of Phoenix dactylifera Pollen in Male Rats

机译：凤梨花粉水提物对雄性大鼠的壮阳活性

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Aim of study: Ancient literature alluded to the use of a number of plants/preparations as sex enhancer. One of such botanicals is Phoenix dactylifera in which the pollen grain has been acclaimed to be used as an aphrodisiac. However, the validity has not been scientifically tested. Dopamine is known to facilitate male sexual function. Therefore, the present study was undertaken to evaluate the effect of aqueous extract of Phoenix dactylifera pollen on the sexual behavior of male rats and to measure of serum Estradiol and Testostrone. Also, dopamine transmission in the nucleus accumbence (NAc) was studied in male rats using in vivo microdialysis. Methods and Materials: sixty male rats were randomized into 6 groups (A-F). Group A received 0.2 ml of Normal Saline mixed with Dimethyl Sulphate (DMSO), while groups B-F were injected same volume containing 35 mg/kg, 70 mg/kg, 105 mg/kg, 140 mg/kg and 350 mg/kg of DPP extract, respectively. Sexual behavioral parameters including mounting, intromission and ejaculation frequencies and latencies were recorded in male rats one hour after injection of extract by mating with a receptive female (1:1). The male serum testosterone and estradiol concentrations were also determined. Results: All doses stimulated male sexual behavior. Extract significantly increased mount, ejaculation, intromission frequencies and ejaculation latency in comparison to controlled ones (p 0.001). Mount and intromission latencies significantly reduced (p 0.001). Maximum effect was observed in dose 140 mg/kg. This extract was found to enhance Testestrone, Estradiol and the orientation of males toward female ones by increasing mounting and ano-genital investigatory behavior. Conclusions: Data from this study identified that the aqueous extract of Phoenix dactylifera pollen grain enhanced sexual behaviour in male rats. The improved sexual appetitive behaviour in male rats may be attributed, to the alkaloids, saponins, and or flavonoids since these phytochemicals has engorgement, androgen enhancing. Also, our findings support the traditional use of this plant as acclaimed aphrodisiac and for the treatment of pre-ejaculation and impotency.
机译：研究目的：古代文献暗示使用多种植物/制剂作为性增强剂。这样的植物药之一是Phoenix dactylifera，其中的花粉粒被公认为可以用作壮阳药。但是，有效性尚未经过科学检验。已知多巴胺可促进男性性功能。因此，本研究旨在评价凤凰果粉花粉水提物对雄性大鼠性行为的影响，并测定血清雌二醇和睾丸激素的含量。另外，使用体内微透析法在雄性大鼠中研究了多巴胺在核伏度（NAc）中的传递。方法和材料：60只雄性大鼠随机分为6组（A-F）。 A组接受0.2 ml生理盐水和硫酸二甲酯（DMSO）混合，而BF组注射相同体积的DPP，分别为35 mg / kg，70 mg / kg，105 mg / kg，140 mg / kg和350 mg / kg分别提取。通过与雌性雌性交配（1：1），在注射提取物一小时后，在雄性大鼠中记录了性行为参数，包括坐骑，内射，射精频率和潜伏期。还测定了男性血清睾丸激素和雌二醇的浓度。结果：所有剂量刺激男性性行为。与对照相比，提取物显着增加了坐骑，射精，射精频率和射精潜伏期（p 0.001）。坐骑和坐骑的潜伏期大大减少（p 0.001）。剂量为140 mg / kg时观察到最大效果。发现该提取物可通过增加坐骑和生殖器生殖器的行为来增强睾丸激素，雌二醇和使男性朝向女性的方向。结论：这项研究的数据表明，凤凰果粉花粉的水提物增强了雄性大鼠的性行为。雄性大鼠性欲改善的行为可能归因于生物碱，皂苷和或类黄酮，因为这些植物化学物质具有充盈和雄激素增强的作用。同样，我们的发现支持该植物作为赞誉的壮阳药的传统用途，并用于治疗射精前和阳imp。

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