• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>African Technology Development Forum Journal >A focus on Malaria in the News
【24h】

A focus on Malaria in the News

机译：新闻中对疟疾的关注

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Chloroquine Is Born Again Chloroquine - which is far cheaper than more modern malaria drugs - was hugely successful in combating the disease when launched in the 1950s – it works by blocking the way the parasite breaks down human haemoglobin contained in red blood cells. But the malaria parasite gradually became resistant to Chloroquine. The resistant forms of the parasite neutralise the drug by developing a mechanism that drains chloroquine away from the key area, preventing it from reaching the necessary concentration. Researchers have found combining the chloroquine with another preparation, Primaquine, seems to restore its effect. Combination of chloroquine with chlorpheniramine proved effective in treating children and pregnant women with chloroquine-resistant infections.
机译：氯喹重生氯喹-比更现代的疟疾药物便宜得多-于1950年代投放市场后，在抗击该疾病方面取得了巨大成功-它通过阻止寄生虫分解红细胞中的人类血红蛋白的方式起作用。但是疟原虫逐渐对氯喹产生抗药性。寄生虫的抗药性形式通过开发一种将氯喹从关键区域排出的机制来中和药物，从而防止其达到必要的浓度。研究人员发现将氯喹与另一种制剂Primaquine结合使用似乎可以恢复其作用。氯喹与氯苯那敏的组合被证明可有效治疗对氯喹耐药的儿童和孕妇。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号