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首页> 外文期刊>African Journal of Biotechnology >Monosodium glutamate: Potentials at inducing prostate pathologies in male Wistar rats
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Monosodium glutamate: Potentials at inducing prostate pathologies in male Wistar rats

机译：谷氨酸钠：诱导雄性Wistar大鼠前列腺病理的潜力。

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摘要

The potential of varying doses of monosodium glutamate (MSG) at altering the functional capacity of the prostate, and the possible role of increasing the concentration of either MSG or distilled water (DW) on such alteration were examined. To achieve these, adult male Wistar rats were treated daily and orally with MSG (5 and 10 mg/kg of body weight (BW)) and DW (1 and 2 ml/kg BW). After 28 days of treatment, the tested doses of MSG significantly elevated the serum total acid phosphatase (TAP) and prostatic acid phosphatase (PAP) activities. Increasing the concentration of either DW or MSG elicited a quantitative but opposing influence on the serum TAP and PAP activities. Thus, medium-term ingestion of MSG might adversely alter the functional capacity of the prostate. The health implication of the alteration could be compounded by the opposing response elicited by increasing the concentration of either MSG or DW.
机译：研究了改变剂量的谷氨酸钠（MSG）改变前列腺功能的潜力，以及在这种改变中增加味精或蒸馏水（DW）浓度的可能作用。为了达到这些目的，每天对成年雄性Wistar大鼠进行口服和口服MSG（5和10 mg / kg体重（BW））和DW（1和2 ml / kg BW）治疗。治疗28天后，测试剂量的味精显着提高了血清总酸性磷酸酶（TAP）和前列腺酸性磷酸酶（PAP）的活性。 DW或MSG浓度的增加对血清TAP和PAP活性产生了定量但相反的影响。因此，中期摄入味精可能会不利地改变前列腺的功能。改变对健康的影响可能与增加味精或DW浓度引起的对立反应有关。

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