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首页> 外文期刊>African Journal of Biotechnology >Evaluation of antioxidant capacity and membrane stabilizing potential of stem and root of Cyphospenna adenocaulis (Steud)
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Evaluation of antioxidant capacity and membrane stabilizing potential of stem and root of Cyphospenna adenocaulis (Steud)

机译：紫茎泽兰茎和根的抗氧化能力和膜稳定潜力的评价

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Comparative analyses of the antioxidant and membrane stabilizing activities of ethanolic extracts of leaf and root of Cyphospenna adenocaulis (Steud) were investigated with a view to further investigate the biological activities of the plant. Both the leaf and root of C. adenocaulis were extracted with 70% ethanol to yield the ethanolic leaf extract (ELE) and ethanolic root extract (ERE) respectively. Phytochemical analyses of the ELE and ERE revealed the presence of flavonoids, tannins, saponins and cardiac glycosides while alkaloids were present in the ERE. The total phenolic and flavonoid contents of the ELE was estimated as 108.0 ± 0.27 mg/g TAE (tannic acid equivalent) and 33.4± 0.32 mg/g QE (Quercetin equivalent) while the ERE contained 182.6 ±0.38 mg/g TAE and 103± 0.43 mg/g QE, respectively. The antioxidant activities of ELE and ERE were investigated using various in vitro assay systems. Both extract exhibited dose-dependent DPPH radical scavenging activity, appreciable reducing power and inhibition of lipid peroxidation in bovine liver homogenate. ELE and ERE were able to protect red blood cell (RBC) membrane against hypotonic and heat induced lyses in a concentration dependent manner. The modes of action were monophasic at various concentrations assayed and were comparable to the standard non-steroidal anti-inflammatory drug used as positive control. The extracts (ELE and ERE) of C. adenocaulis possess appreciable and potent antioxidant and membrane stabilization potentials, however, the ERE displayed a stronger antioxidant and membrane stabilizing activities.
机译：为了进一步研究植物的生物学活性，对烟叶拟南芥叶和根的乙醇提取物的抗氧化剂和膜稳定活性进行了比较分析。用70％乙醇提取紫茎泽兰的叶和根，分别得到乙醇叶提取物（ELE）和乙醇根提取物（ERE）。 ELE和ERE的植物化学分析表明，ERE中存在生物碱，但存在类黄酮，单宁，皂角苷和强心苷。 ELE的总酚和类黄酮含量估计为108.0±0.27 mg / g TAE（鞣酸当量）和33.4±0.32 mg / g QE（槲皮素当量），而ERE包含182.6±0.38 mg / g TAE和103± QE分别为0.43 mg / g。使用各种体外测定系统研究了ELE和ERE的抗氧化活性。两种提取物均表现出剂量依赖性的DPPH自由基清除活性，可观的还原能力和对牛肝匀浆中脂质过氧化的抑制作用。 ELE和ERE能够以浓度依赖性的方式保护红细胞（RBC）膜免受低渗和热诱导的裂解作用。作用模式在各种浓度下都是单相的，与用作阳性对照的标准非甾体类抗炎药相当。腺藻的提取物（ELE和ERE）具有明显而有效的抗氧化剂和膜稳定潜力，但是ERE表现出更强的抗氧化剂和膜稳定活性。

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