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首页> 外文期刊>African Journal of Biotechnology >Study of anti-inflammatory, anti-diabetic, and analgesic activity of Oscillatoria annae extract in rats and mice
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Study of anti-inflammatory, anti-diabetic, and analgesic activity of Oscillatoria annae extract in rats and mice

机译：拟南芥（Oscillatoria annae）提取物在大鼠和小鼠中的抗炎，抗糖尿病和镇痛作用研究

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摘要

The aqueous extract of the cyanobacterium?Oscillatoria annae?was investigated for its anti-inflammatory, anti-diabetic,analgesic and cholesterol regulating properties in different experimental standard animal models. The non-steroidal anti-inflammatory drug, indomethacin (10 mg/kg/body?weight) was used as standard in the anti-inflammatory, and analgesic studies, while glibenclamide (600?μg/kg/b.wt.) was used as standard drug in the anti-diabetic study. The results reveal that?O. annae?possesses significant ameliorating effects in the studied animal models, including rats and mice. These effects were comparable to those obtained after treatment with the standard drugs used in this study. The results indicate that the cyanobacterial extract can act as natural remedy and also open a new avenue to identify the active ingredients behind these effects.
机译：在不同的实验标准动物模型中，对蓝藻细菌Oscillatoria annae的水提取物的抗炎，抗糖尿病，镇痛和胆固醇调节特性进行了研究。非甾体类消炎药消炎痛（10 mg / kg /体重）被用作消炎和止痛研究的标准药物，而格列苯脲（600？μg/ kg / b.wt。）被使用。作为抗糖尿病研究的标准药物。结果表明？安娜在研究的动物模型（包括大鼠和小鼠）中具有明显的改善作用。这些效果可与本研究中使用的标准药物治疗后获得的效果相当。结果表明，蓝藻提取物可以作为天然药物，也为鉴定这些作用背后的活性成分开辟了一条新途径。

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