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首页> 外文期刊>African Journal of Biotechnology >Drug-resistant post-neurosurgical nosocomial Acinetobacter baumannii meningitis in two Iranian hospitals
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Drug-resistant post-neurosurgical nosocomial Acinetobacter baumannii meningitis in two Iranian hospitals

机译：伊朗两家医院的耐药性神经外科手术后医院鲍曼不动杆菌脑膜炎

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摘要

Acinetobacter baumannii?may cause meningitis and ventriculitis, particularly after head trauma and/or neurosurgery. The rate of multidrug-resistant?Acinetobactermeningitis has increased over the past years. This study was conducted to determine prevalence of drug-resistant post-neurosurgical nosocomial?A. baumannii?meningitis. During the period of study between 2007 and 2009, a total of?39 patients with positive culture of?A. baumannii?in their cerebrospinal fluid were evaluated. Standard bacteriological methods were used for identification of?A. baumannii.?The method which has been recommended by Clinical Laboratory and Standards Institute (CLSI) was applied to determine susceptibility and resistant pattern.?All patients had a history of neurosurgical intervention and more than half of them stayed in the intensive care units (ICU) at the time of isolation. The highest rate of resistant pattern accounted for the third generation cephalosporins, followed by ciprofloxacin, amikacin, gentamicin and co-terimoxazole. Of all the isolates, 39% were resistant to imipenem and 15.5% to meropenem. The majority of carbapenem-resistant isolates were resistant to at least three other antibiotic classes. The emergence of postsurgical multi-drug resistant?Acinetobacter?meningitis highlights the importance of implementing preventative strategies towards nosocomial infections.
机译：鲍曼不动杆菌可能引起脑膜炎和脑室炎，尤其是在头部外伤和/或神经外科手术之后。在过去几年中，多重耐药性不动杆菌脑膜炎的发病率有所上升。进行这项研究是为了确定耐药性神经外科手术后医院内感染的发生率。鲍曼氏脑膜炎。在2007年至2009年的研究期间，共有39例A阳性培养患者。对他们的脑脊液中的鲍曼不育进行了评估。用标准细菌学方法鉴定ΔA。 baumannii。采用临床实验室和标准协会（CLSI）推荐的方法确定药敏性和耐药性模式。所有患者都有神经外科手术史，其中一半以上留在重症监护室（ICU） ）隔离时。耐药模式发生率最高的是第三代头孢菌素，其次是环丙沙星，丁胺卡那霉素，庆大霉素和复方新诺明。在所有分离株中，有39％对亚胺培南有抗性，对美罗培南有15.5％的抗性。大多数对碳青霉烯类耐药的菌株对至少三种其他抗生素类耐药。术后多重耐药性不动杆菌脑膜炎的出现凸显了对医院感染实施预防策略的重要性。

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