首页> 外文期刊>African Journal of Biotechnology >Preliminary phytochemical, antimicrobial and acute toxicity studies of the stem, bark and the leaves of a cultivated Syzygium cumini Linn. (Family: Myrtaceae) in Nigeria
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Preliminary phytochemical, antimicrobial and acute toxicity studies of the stem, bark and the leaves of a cultivated Syzygium cumini Linn. (Family: Myrtaceae) in Nigeria

机译:栽培的Syzygium cumini Linn茎,树皮和叶子的初步植物化学,抗微生物和急性毒性研究。 (家庭:桃金娘科)在尼日利亚

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The phytochemical, antimicrobial and acute toxicity studies of the leaf and stem bark extracts of?Syzygium cumini?Linn. grown in Abuja, Nigeria was carried out. The phytochemical screening revealed the presence of carbohydrates, saponins, tannins, terpenes, volatile oil, sterols, resins balsam, phlobatanins and flavonoids in the leaves and stem bark of the species studied. Alkaloids and anthraquinones were absent in all the plant parts studied. 70% methanol extracts were used for antimicrobial and acute toxicity studies. The six test organisms used for antimicrobial studies were:?Pseudomonas auriginosa, Escherichia coli, Staphylococcus aureus, Candida albicans, Bacillus subtilis and Salmonella typhii.The oil from the leaves showed activity on all the test organisms; the leaf extract showed activity on?all test organisms except?P. auriginosa?while the stem bark extract showed no activity on any of the test organisms used. The oil had a saponification value of 363 and an acid value of 4.21. The lethal dose 50% (LD50) in mice was found to be >5000 mg/kg for the stem bark and at 3,873 mg/kg for the leaf extracts.
机译:枯草Syzygium cumini?Linn的叶和茎皮提取物的植物化学,抗微生物和急性毒性研究。进行了在尼日利亚阿布贾的种植。植物化学筛选显示,所研究物种的叶子和茎皮中存在碳水化合物,皂角苷,单宁,萜烯,挥发油,固醇,树脂香脂,叶黄酮和类黄酮。研究的所有植物部位均没有生物碱和蒽醌。 70%的甲醇提取物用于抗微生物和急性毒性研究。用于抗菌研究的六种受试微生物是:绿假单胞菌,大肠杆菌,金黄色葡萄球菌,白色念珠菌,枯草芽孢杆菌和鼠伤寒沙门氏菌。叶提取物对除P以外的所有测试生物均显示活性。茎皮提取物对所用的任何测试生物均无活性。该油的皂化值为363,酸值为4.21。发现小鼠的50%致死剂量(LD50)对茎皮为> 5000 mg / kg,对叶提取物为3873 mg / kg。

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