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首页> 外文期刊>African Journal of Biotechnology >Evaluation of androgenic activity of Mucuna pruriens in male rats
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Evaluation of androgenic activity of Mucuna pruriens in male rats

机译：毛uc虫雄性大鼠雄激素活性的评价

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摘要

Methanolic extract of?Mucuna pruriens?seed was tested for their possible androgenic activity in Wister male albino rats. The methanolic extract of?M. pruriensplant was gavaged separately into 2 group of rat at similar doses of 1000 mg/kg b.wt and 1500 mg/kg b.wt for 30 days. At the end of the treatment, the animals were killed and the blood, testis, epididymis, seminal vesicles and prostate were collected for biochemical analysis. The methanolic extracts of?M. prurienssignificantly increased the relative weight of the testis, serum and testicular testosterone level, testicular cholesterol level, protein level in the testis and epididymis, and epididymal alkaline phosphatase activity. The methanolic extracts of?M. pruriens?possess androgenic activity.
机译：测试了M菜（Mucuna pruriens）种子的甲醇提取物在维斯特雄性白化病大鼠中可能的雄激素活性。甲醇的甲醇提取物。将pruriensplant分别以相似的剂量分别以1000 mg / kg b.wt和1500 mg / kg b.wt分成两组，共30天。治疗结束时，处死动物，收集血液，睾丸，附睾，精囊和前列腺进行生化分析。甲醇的甲醇提取物。明显增加了睾丸的相对重量，血清和睾丸睾丸激素水平，睾丸胆固醇水平，睾丸和附睾中的蛋白质水平以及附睾碱性磷酸酶活性。甲醇的甲醇提取物。瘙痒症具有雄激素活性。

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