• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>African Journal of Biotechnology >Second derivative spectrophotometric determination of cyclophosphamide in pharmaceutical formulations
【24h】

Second derivative spectrophotometric determination of cyclophosphamide in pharmaceutical formulations

机译：二阶分光光度法测定药物制剂中的环磷酰胺

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

A new, simple, rapid, wide applicable range and reliable second derivative spectrophotometric method has been developed for determination of cyclophosphamide (CP) in bulk and pharmaceutical dosage forms. Calibration graph is linear in the concentration range of 25 - 200 μg/ml of CP with 10 μg/ml of detection limit and correlation coefficient of 0.9976. The precision and accuracy were acceptable depending upon the values of relative standard deviation and error percentage. Developed second derivative spectrophotometric method can be directly and easily applied for analyzing pure form and commercial pharmaceutical preparations of CP. The method was compared with a standard high performance liquid chromatography (HPLC) method and can be used for the quality control of pharmaceutical preparations in Erbil City.
机译：已经开发了一种新的，简单，快速，适用范围广且可靠的二阶导数分光光度法，用于测定散装和药物剂型中的环磷酰胺（CP）。校准曲线在25-200μg/ ml CP的浓度范围内是线性的，检测限为10μg/ ml，相关系数为0.9976。根据相对标准偏差和误差百分比的值，精度和准确性是可以接受的。所开发的二阶导数分光光度法可以直接简便地用于分析CP的纯形式和商业药物制剂。该方法与标准高效液相色谱（HPLC）方法进行了比较，可用于埃尔比勒市药物制剂的质量控制。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号