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首页> 外文期刊>African Journal of Cellular Pathology >A STUDY OF ULCER INDUCED STOMACH OF ALBINO RATS TREATED WITH IDOGU MIXTURE, A POTENT ANTI-ULCER HERBAL DRUG
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A STUDY OF ULCER INDUCED STOMACH OF ALBINO RATS TREATED WITH IDOGU MIXTURE, A POTENT ANTI-ULCER HERBAL DRUG

机译：抗溃疡药草本IDOGU混合物治疗白化病大鼠溃疡诱发的气孔的研究

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Aim: The aim of this study was to assess the potency of the anti-ulcer drug, Idogun on the stomach of ulcer induced albino rats.Method: Six groups of locally bred albino rats were used. Each group containing five rats of either sex were orally treated respectively with distilled water (ulcer control group), omeprazole 20mg/kg (reference group) and 100, 200, 400 and 800mg/kg extract of Idogun anti –ulcer mixture (experimental group). Rats were sacrificed one hour after oral administration of 1ml absolute ethanol to induce injury in the gastric mucosa.Results: Tissue sections from ulcer induced rats contained haemorrhage, dense infiltration by mixed inflammatory cells and extensive ulceration. These features were absent in the ulcer induced rats that were subsequently treated with the Idogun mixture. Mild tissue edema and presence of inflammatory cells were observed in the omeprazole treated section.Conclusion: Idogun anti-ulcer herbal mixture is a potent anti-ulcer drug.
机译：目的：本研究的目的是评估抗溃疡药物伊多贡（Idogun）在溃疡性白化病大鼠胃中的功效。方法：使用六组本地繁殖的白化病大鼠。每组各有五只大鼠，分别用蒸馏水（溃疡对照组），奥美拉唑20mg / kg（参考组）和100、200、400和800mg / kg的Idogun抗溃疡混合物提取物（实验组）口服治疗。 。口服1ml的无水乙醇一小时后处死大鼠，引起胃粘膜损伤。结果：溃疡诱导大鼠的组织切片出血，混合炎性细胞密集浸润和广泛溃疡。这些特征在溃疡诱导的大鼠中不存在，随后用伊多贡混合物治疗。在奥美拉唑治疗部位观察到轻度的组织水肿和炎性细胞的存在。结论：益多酮抗溃疡草药混合物是一种有效的抗溃疡药物。

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