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Acute toxicity and haematological changes in common carp (Cyprinus carpio) caused by diazinon exposure

机译:二嗪农暴露引起的鲤的急性毒性和血液学变化

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The common carp (Cyprinus carpio) was exposed to diazinon to determine the lethal concentration (LC50) values at different times and effects of sub-lethal concentrations on haematological and biochemical parameters. The LC50?values at varying times were recorded as high as 18.57 mg/l (24 h), 14.87 mg/l (48 h), 12.29 mg/l (72 h) and 9.76 mg/l (96 h). Fishes exposed to sub-lethal concentrations (0.5, 1.0 and 2.0 mg/l) for four weeks revealed that the pesticide causes alterations in various blood parameters. Red blood cell (RBC) counts, haemoglobin concentration and haematocrit values increased whereas white blood cell (WBC) count decreased. Plasma glucose level, glutamate-oxaloacetate transminase (PGOT) and plasma glutamate pyruvate transminase (PGPT) activities increased in the fish exposed to diazinon. Protein level in plasma and glycogen in liver and muscles were found to decrease in treated fish with diazinon.?? ????keyword:?Bioassay, Biochemical and Haematological Changes, Diazinon,Cyprinus carpio.
机译:将鲤鱼(Cyprinus carpio)暴露于二嗪农以测定不同时间的致死浓度(LC50)值以及亚致死浓度对血液和生化参数的影响。在不同时间记录的LC50值分别高达18.57 mg / l(24小时),14.87 mg / l(48小时),12.29 mg / l(72小时)和9.76 mg / l(96小时)。暴露于亚致死浓度(0.5、1.0和2.0 mg / l)达四个星期的鱼表明,该农药引起各种血液参数的改变。红细胞(RBC)计数,血红蛋白浓度和血细胞比容值增加,而白细胞(WBC)计数减少。暴露于二嗪农的鱼的血浆葡萄糖水平,谷氨酸-草酰乙酸转氨酶(PGOT)和血浆谷氨酸-丙酮酸转氨酶(PGPT)活性增加。发现用二嗪农处理的鱼血浆中蛋白质水平以及肝和肌肉中糖原的含量降低。关键字:生化分析,生化和血液学变化,Diazinon,鲤鱼。

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