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首页> 外文期刊>American journal of applied sciences >Utility of Certain ? Acceptors for Spectrophotometric Determination of Sildenafil Citrate | Science Publications
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Utility of Certain ? Acceptors for Spectrophotometric Determination of Sildenafil Citrate | Science Publications

机译：某些实用程序？分光光度法测定柠檬酸西地那非的受体科学出版物

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> Sildenafil citrate was determined through charge transfer complexes (CTC) formation with three electron acceptor reagents. The methods involve the reaction of Sildenafil citrate as n-donor with either Chloranil (tetrachloro 1,4-benzoquinone), tetracyanoethylene (TCNE) or 7,7,8,8-tetracyanoquinodimethane (TCNQ) as n-acceptors, to give a stable and highly colored radical anion. The colored products were quantified spectrophotometrically. The condition ranges adhering to Beer's law are 0.05-3.00 mg/ml. The molar ratios of the reactants were ascertained. The different parameters were carefully studied and optimized. Statistical analysis of the results revealed equal precision and accuracy to the results of the reported method. The methods were applied for determination of sildenafil citrate in pure form and in Viagra tablets.
机译： >柠檬酸西地那非是通过与三种电子受体试剂的电荷转移络合物（CTC）形成而确定的。该方法包括将柠檬酸西地那非作为正给体与氯腈（四氯1,4-苯醌），四氰基乙烯（TCNE）或7,7,8,8-四氰基喹二甲烷（TCNQ）作为正受体反应，得到稳定的化合物。和高度着色的自由基阴离子。分光光度法定量着色的产物。遵守比尔定律的条件范围是0.05-3.00 mg / ml。确定反应物的摩尔比。仔细研究和优化了不同的参数。结果的统计分析表明，与所报告方法的结果具有同等的准确性和准确性。该方法适用于测定纯形式和伟哥片剂中柠檬酸西地那非的含量。

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