Successful reversal of bupivacaine and lidocaine-induced severe junctional bradycardia by lipid emulsion following infraclavicular brachial plexus block in a uremic patient

Yu-Hsuan Shih; Chen-Hsiu Chen; Ying-Ming Wang; Kang Liu

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Successful reversal of bupivacaine and lidocaine-induced severe junctional bradycardia by lipid emulsion following infraclavicular brachial plexus block in a uremic patient

机译：尿毒症患者锁骨下臂丛神经阻滞后脂质乳剂成功逆转布比卡因和利多卡因诱导的重度交界性心动过缓

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Cardiac toxicity of bupivacaine has long been documented and it could be potentiated in certain circumstances, such as preexisting cardiac conduction abnormality or uremic status. The concept that lipid emulsion acts as a rescue of bupivacaine's toxicity has prevailed pending universal recognition. Herein, we report the successful use of lipid to resuscitate a female uremic patient who sustained junctional bradycardia while she was receiving ultrasound-guided infraclavicular brachial plexus block with the dose of local anesthetics far below the currently recommended maximum one. The possible mechanisms for the occurrence of cardiotoxicity in this case are discussed and the role of lipid emulsion as a treatment is reviewed.

机译：布比卡因的心脏毒性已有很长的文献记载，在某些情况下，如先前存在的心脏传导异常或尿毒症状态，可能会增强这种毒性。脂质乳液可以挽救布比卡因的毒性这一概念已得到普遍认可。在本文中，我们报道了脂质的成功使用，使一位在接受超声引导下的锁骨下臂丛神经阻滞且持续麻醉剂量低于目前推荐的最大剂量的持续性连接性心动过缓的女性尿毒症患者中复苏。讨论了在这种情况下发生心脏毒性的可能机制，并综述了脂质乳剂作为治疗的作用。

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《Acta anaesthesiologica Taiwanica :》 |2011年第2期|共3页
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Yu-Hsuan Shih; Chen-Hsiu Chen; Ying-Ming Wang; Kang Liu;
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1. The Extent of Blockade Following Axillary and Infraclavicular Approaches of Brachial Plexus Block in Uremic Patients [J] . Damla Sariguney, Ahmet Mahli, Demet Coskun Journal of Clinical Medicine Research . 2012,第1期

机译：尿毒症患者臂丛神经丛腋窝和锁骨下入路后的阻塞程度
2. Comparison of Single-Dose Infraclavicular Brachial Plexus Block and Continuous Infraclavicular Brachial Plexus Block Applications in the Treatment of Finger Amputations [J] . Journal of hand and microsurgery . 2019,第3期

机译：单剂量Infroadlavicular臂丛丛块和连续血管臂丛神经块应用在手指截肢中的应用
3. The infraclavicular brachial plexus block by the coracoid approach is clinically effective: an observational study of 150 patients: (Le bloc infraclaviculaire du plexus brachial, realise par l'approche coracoide, est efficace sur le plan clinique : u [J] . Desroches J Canadian journal of anesthesia: Journal canadien d'anesthesie . 2003,第3期

机译：通过喙突入路锁骨下臂丛神经阻滞在临床上是有效的：一项对150例患者的观察性研究：
4. Combined Paravertebral Lumbar Plexus, Sciatic Nerve and Iliac Crest Block for Reduction and Instrumentation of Hip Fractures in Elderly Patients with Moderate to Severe Aortic Stenosis [C] . Wong KK, Ling KU, Shariffuddin I. I., ASEAN Congress of Anesthesiologists . 2009

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5. The Effect of Intraoperative Esmolol Administration on Opioid Requirements in the Post Anesthesia Care Unit in Patients with a Continuous Low Volume Interscalene Brachial Plexus Nerve Block [D] . Fister, Rachel M. 2018

机译：术中给予艾司洛尔对持续小容量间斜肌间臂臂丛神经阻滞患者麻醉后监护室中阿片类药物需求的影响
6. The Extent of Blockade Following Axillary and Infraclavicular Approaches of Brachial Plexus Block in Uremic Patients [O] . Damla Sariguney, Ahmet Mahli, Demet Coskun 2012

机译：尿毒症患者臂丛神经丛腋窝和锁骨下入路后的阻滞程度
7. The Extent of Blockade Following Axillary and Infraclavicular Approaches of Brachial Plexus Block in Uremic Patients [O] . Sariguney, Damla, Mahli, Ahmet, Coskun, Demet 2012

机译：尿毒症患者臂丛神经丛腋窝和锁骨下入路后的阻滞程度

Successful reversal of bupivacaine and lidocaine-induced severe junctional bradycardia by lipid emulsion following infraclavicular brachial plexus block in a uremic patient

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