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Peribulbar block in 500 patients scheduled for eye procedures and treated with acetyl salicylic acid

机译:计划进行眼部手术并接受乙酰水杨酸治疗的500名患者的眼球周围传导阻滞

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Objectives: No guidelines are available in France for peribulbar block for eye procedures. It is our hypothesis that continued use of acetyl salicylic acid for forestalling myocardial or cerebrovascular ischemic events does not increase the risk of hemorrhage, compared with discontinuation of its use in patients who undergo eye procedures under peribulbar block. Methods: For this prospective control study we enrolled two groups of 500 patients scheduled for intra-ocular eye surgery requiring a peribulbar block. Patients treated with acetyl salicylic acid were included in group A (500 patients). Patients who had never been treated with acetyl salicylic acid constituted the control group (group B: 500 patients). Hemorrhages were graded as follows: 1=spot ecchymosis; 2=lid ecchymosis involving half of the lid surface area or less; 3=lid ecchymosis all around the eye, without increase in intra-ocular pressure; 4=retrobulbar hemorrhage with increased intraocular pressure. Results: In group A, lid hemorrhages (grade 1) were observed in 30 patients (6.0%). No grade 2, 3 or 4 hemorrhages were encountered in this group. In group B, lid hemorrhage (grade 1) was observed in 20 patients (4.0%) and grade 2 in one patient (0.2 %), but no grade 3 or 4 hemorrhages were encountered. Statistical tests showed the absence of significance between both groups. Conclusion: We conclude that between the groups with and without pre-operative acetyl salicylic acid the occurrence rate of lid hemorrhage was not significant in peribulbar block.
机译:目标:法国尚无针对眼球周围障碍的指南。我们的假设是,与在眼球周围阻塞下进行眼部手术的患者停止使用乙酰水杨酸相比,继续使用乙酰水杨酸预防心肌或脑血管缺血事件不会增加出血的风险。方法:对于这项前瞻性对照研究,我们纳入了两组500名患者,这些患者计划进行眼球手术,需要进行眼球周围阻滞。 A组包括接受乙酰水杨酸治疗的患者(500名患者)。从未接受乙酰水杨酸治疗的患者为对照组(B组:500名患者)。出血分级如下:1 =斑点瘀斑; 2 =涉及盖表面积的一半或更少的睑瘀斑; 3 =眼睑周围全瘀斑,眼内压没有增加; 4 =眼球内压增加引起的眼球出血。结果:在A组中,有30例患者(6.0%)观察到眼睑出血(1级)。该组未发生2、3或4级出血。在B组中,观察到20例患者(4.0%)发生眼睑出血(1级),而1例患者(0.2%)发生2级眼睑出血,但未见3或4级出血。统计检验表明两组之间均无显着性。结论:我们得出结论,在术前和不术前使用乙酰水杨酸的组之间,眼睑周围闭塞的眼睑出血发生率不显着。

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