Novel drug delivery systems have several advantages over conventional multi dose therapy. Recent trends indicate that micro particulate drug delivery systems are especially suitable for achieving controlled or delayed release oral formulations with low risk of dose dumping, flexibility of blending to attain different release patterns as well as reproducible and short gastric residence time. The release of drug from micro particles depends on a variety of factors including the carrier used to form the micro particles and the amount of drug contained in them. Consequently, micro particulate drug delivery systems provide tremendous opportunities for designing new controlled and delayed release oral formulations, thus extending the frontier of future pharmaceutical development. One such approach is using microspheres as carriers for drugs. A well-designed controlled drug delivery system can overcome some of the problems of conventional therapy and enhance the therapeutic efficacy of a particular drug. It is the reliable mean to deliver the drug to the target site with specificity, if modified and to maintain the desired concentration at the site of interest without untoward effects. Microspheres received much attention not only for prolonged release but also for targeting of anticancer drugs to the tumor.
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