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首页> 外文期刊>American Journal of Cancer Prevention >Experience for Management of Surgical Treatment in Patients with Carcinomas of the Pancreatic Head or Periampullary Region
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Experience for Management of Surgical Treatment in Patients with Carcinomas of the Pancreatic Head or Periampullary Region

机译：胰头或壶腹周围癌患者手术治疗管理的经验

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Objective: Pancreaticoduodenectomy was considered as the standard choice of surgery treatment to carcinomas in the pancreatic head or periampullary region. This study will focus on the experience summary to manage the patients with carcinomas in the pancreatic head or periampullary region who underwent surgery treatment in west area of China to investigate the different surgical methods, prognosis and long term survival. Method: We consecutively reviewed 73 patients underwent surgery treatment in our hospital between January 2007 and December 2011. Surgery treatment described as radical operation of PD treatment and palliative operation of choledochojejunostomy plus drainage. We assessed different variables to summarize the management of patients and to evaluate the long term survival. Result: 32 patients received PD treatment and 41 patients received palliative surgery treatment. Histologic diagnosis indicated that all patients had malignant disease. PD procedures spent more time to complete the operation. 3 patients in PD group developed pancreatic fistula and 1 of them died on the seventh days postoperative. 2 patients developed wound infection and 1 patient developed malnutrition which finally reversed by medical intervention. The postoperative mortality in PD group was observed in 2 of 32 patients. The postoperative mortality in PD group was 6.25% (n=2). Long term survival of PD and palliative surgery group was described as 15.4 months and 5.6 months respectively. Conclusion：The treatment of patients with carcinomas in the pancreatic head or periampullary region continues to be associated with high incidence of postoperative complicatons. Early diagnosis and pancreaticoduodenectomy represents the only possibility of cure.
机译：目的：胰十二指肠切除术被认为是胰头或壶腹周围区域癌的手术治疗的标准选择。本研究将重点总结经验总结，以管理在中国西部地区接受手术治疗的胰头或壶腹周围区域的癌症患者，以研究不同的手术方法，预后和长期生存。方法：我们连续回顾了2007年1月至2011年12月在我院接受手术治疗的73例患者。手术治疗被描述为PD的根治性手术和胆总管空肠吻合加引流的姑息性手术。我们评估了不同的变量，以总结患者的治疗并评估长期生存率。结果：32例接受PD治疗，41例接受姑息手术治疗。组织学诊断表明所有患者均患有恶性疾病。 PD程序花费了更多时间来完成操作。 PD组3例出现胰瘘，术后1天死亡1例。 2例出现伤口感染，1例出现营养不良，最终通过医疗干预得以逆转。 PD组32例中有2例术后死亡。 PD组的术后死亡率为6.25％（n = 2）。 PD和姑息性手术组的长期生存分别被描述为15.4个月和5.6个月。结论：胰头或壶腹周围癌的治疗仍与术后并发症高发有关。早期诊断和胰十二指肠切除术是治愈的唯一可能性。

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