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首页> 外文期刊>American Journal of PharmTech Research >Study of wound healing activity of Delonix regia flowers in experimental animal models
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Study of wound healing activity of Delonix regia flowers in experimental animal models

机译:地龙(Delonix regia)花在实验动物模型中的伤口愈合活性研究

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  ABSTRACT Delonix regia, a well known plant with high medicinal value, reported to have a number of biological activities including antioxidant, and presence of flavonoids in its chemical constituents. Antioxidant property and flavonoids have been associated with wound healing actions of plants. The present study was done to investigate the wound healing properties of Delonix regia in experimental animal models. The ethanolic and aqueous extracts of Delonix regia flowers were prepared to study the effect on wound healing in albino rats using incision and excision wound models. Healing was assessed by the rate of wound contraction, period of epithelialisation, tensile strength (skin breaking strength) and estimation the hydroxyproline content. The extracts significantly promoted the healing process, as evident by an increase in wound breaking strength, percentage of wound contraction, increased hydroxyproline content and decreased epithelialisation period, suggesting the possible utilization of this plant to enhance wound healing. Key words: Delonix regia, flowers, extract, wound.
机译:摘要Delonix regia是一种具有高药用价值的著名植物,据报道具有许多生物活性,包括抗氧化剂和其化学成分中存在黄酮类化合物。抗氧化剂和类黄酮与植物的伤口愈合作用有关。进行本研究以研究Delonix regia在实验动物模型中的伤口愈合特性。制备了Delonix regia花的乙醇提取物和水提取物,以研究使用切口和切除伤口模型对白化病大鼠伤口愈合的影响。通过伤口收缩率,上皮化时间,抗张强度(皮肤断裂强度)和估计羟脯氨酸含量来评估愈合情况。提取物显着促进了愈合过程,如伤口断裂强度的提高,伤口收缩的百分比,羟脯氨酸含量的增加和上皮化时间的缩短所表明的,表明该植物可能被用于增强伤口愈合。关键词:德龙,花,提取物,伤口。

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