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Association Between Pet Ownership and the Sensitization to Pet Allergens in Adults With Various Allergic Diseases

机译:宠物所有权与成人各种过敏性疾病的宠物过敏原敏感性之间的关联

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Purpose As pet ownership increases, sensitization to animal allergens due to domestic exposure is a concern. Sensitization to animal allergens may occur from indirect exposure, as well as direct ownership of animals. However, there have been conflicting results regarding the association between pet ownership and sensitization to animal allergens in adults. Methods In total, 401 patients with various allergic diseases were enrolled in this study. We performed skin prick tests with 55 common inhalant and food allergens, including dog, cat, and rabbit allergens. A mean wheal diameter of 3 mm or greater was considered a positive reaction. The exposure modality to each animal allergen was investigated using a questionnaire and included present ownership, past ownership, occupational exposure, occasional exposure, contact with pet owner, and no contact. Present ownership, past ownership, occupational, and occasional exposure were regarded as direct exposure. Results The sensitization rate for animal allergens was 20.4% for dog, 15.0% for cat, and 9.0% for rabbit. Direct exposure to dogs (72.0%) was significantly higher than that of other animals (18.4% for cats and 16.7% for rabbits), whereas 'no contact' with cats (78.3%) and rabbits (83.3%) was significantly higher than with dogs (26.8%; P Conclusions These results suggest that direct exposure to dogs contributes to the sensitization to dog allergens in patients with allergic diseases, whereas indirect exposure to cats and rabbits may induce sensitization to each animal's allergen.
机译:目的随着宠物拥有量的增加,家庭接触引起的对动物过敏原的敏感性成为一个问题。对动物过敏原的过敏可能源于间接接触以及动物的直接所有权。但是,关于宠物所有权与成人对动物过敏原的敏感性之间的关系,存在着矛盾的结果。方法本研究共纳入401名各种过敏性疾病患者。我们对55种常见的吸入性和食物过敏原(包括狗,猫和兔子过敏原)进行了皮肤点刺测试。平均风团直径为3 mm或更大被认为是阳性反应。使用问卷调查了每种动物过敏原的接触方式,包括现在的所有权,过去的所有权,职业接触,偶发的接触,与宠物拥有者的接触以及无接触。现在的所有权,过去的所有权,职业和偶发的接触被视为直接接触。结果动物过敏原的致敏率是:犬为20.4%,猫为15.0%,兔为9.0%。直接接触狗(72.0%)明显高于其他动物(猫为18.4%,兔子为16.7%),而猫(78.3%)和兔子(83.3%)的“不接触”显着高于猫。狗(26.8%; P结论)这些结果表明,直接接触狗有助于过敏性疾病患者对狗过敏原的致敏,而间接接触猫和兔子则可能引起对每种动物过敏原的致敏。

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