...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>American Journal of PharmTech Research >Studies on Antioxidant Activity, Total Phenolic and Total Flavonoid Contents of Terminalia Catappa Leaves Using In-vitro Models
【24h】

Studies on Antioxidant Activity, Total Phenolic and Total Flavonoid Contents of Terminalia Catappa Leaves Using In-vitro Models

机译：应用体外模型研究榄仁木叶片的抗氧化活性，总酚和总黄酮含量

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

ABSTRACT Plants produce a diverse range of bioactive molecules, making them a rich source of different types of medicines. A regular and widespread use of herbs throughout the world has increased serious concern over their quality, safety and efficacy. Thus, a proper scientific evidence or assessment has become the criteria for acceptance of herbal health claims. In the present study, we examined the antioxidant effects of Terminalia Catappa plant extract. Dried and powered of T. Catappa was extracted with hexane, chloroform, methanol, ethanol and water. Total phenolic and flavonoid contents of different solvent extracts were determined. Of the different solvent extracts, methanol extract had the highest phenol and flavonoid content of 121.9±3.1mg/g and 59.6±1.5mg/g respectively. Antioxidant assays were carried out by using different in vitro models such as total reducing power, total antioxidant activity, lipid peroxidation inhibitory activity, DPPH radical scavenging activity and superoxide radical scavenging activity. methanol extract showed the highest total antioxidant activity of 41.4±0.45 µM Fe(II)/g. The EC50 values of ethanol extract for lipid peroxidation inhibitory activity and DPPH radical scavenging activity was found to be 0.1 and 0.5 mg/ml respectively. The anti-oxidant activities of other solvent extracts were poor when compared to the ethanol extract. These results suggest that, the active antioxidant compounds are better extracted in ethanol and there is a direct correlation between the total polyphenols extracted and its anti-oxidant activity. The invitro anti-oxidant activity of T. Catappa justifies the ethno medical use of this plant. Keywords: Medicinal plant; Terminalia Catappa; solvent extracts; anti-oxidant activity.
机译：摘要植物产生各种各样的生物活性分子，使它们成为不同类型药物的丰富来源。在世界范围内定期广泛使用草药已引起人们对其质量，安全性和功效的严重关注。因此，适当的科学证据或评估已成为接受草药健康声明的标准。在本研究中，我们检查了榄仁木提取物的抗氧化作用。干燥并用丁酸钾干燥。用己烷，氯仿，甲醇，乙醇和水萃取卡塔帕。测定了不同溶剂提取物的总酚和类黄酮含量。在不同的溶剂提取物中，甲醇提取物的最高苯酚和类黄酮含量分别为121.9±3.1mg / g和59.6±1.5mg / g。通过使用不同的体外模型进行抗氧化剂测定，例如总还原能力，总抗氧化剂活性，脂质过氧化抑制活性，DPPH自由基清除活性和超氧化物自由基清除活性。甲醇提取物显示出最高的总抗氧化活性，为41.4±0.45 µM Fe（II）/ g。乙醇提取物对脂质过氧化抑制活性和DPPH自由基清除活性的EC50值分别为0.1和0.5 mg / ml。与乙醇提取物相比，其他溶剂提取物的抗氧化活性很差。这些结果表明，活性抗氧化剂化合物在乙醇中的提取效果更好，并且提取的总多酚与其抗氧化活性之间存在直接关系。 T. Catappa的体外抗氧化活性证明了该植物的民族医学用途。关键词：药用植物; Terminalia Catappa;溶剂提取物;抗氧化活性。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号