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首页> 外文期刊>Advances in Nephrology >Managing End-Stage Renal Disease in Older Patients: A Single Centre Experience with Renal Transplantation in the Elderly
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Managing End-Stage Renal Disease in Older Patients: A Single Centre Experience with Renal Transplantation in the Elderly

机译：处理老年患者的终末期肾脏疾病：老年肾脏移植的单中心经验

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The increase of patients developing end-stage renal disease (ESRD) has occurred predominantly in the older adult population. As a consequence, the nephrologists will need to decide whom of these older patients are siutable for transplantation. There are very few absolute contraindications, such as active infection and recent malignancy, but there are many relative or potential contraindications in older patients. Worldwide, organs available for transplantation are limited. Some centers are reluctant to use organs from expanded criteria donors also in elderly recipients. This leads to long waiting lists and many older patients will die while they are waiting for an organ. It is vital that the patients who are accepted for renal transplantation are those who will derive most benefit, and correct selection of patients and donor organs is therefore of outmost importance. This paper describes the previous and planned research our research group has performed with focus on older renal transplant recipients with special emphasis on survival, basic immunosuppression, selection of organs, and health related quality of life.
机译：发生终末期肾病（ESRD）的患者增加主要发生在老年人群中。结果，肾病医师将需要确定这些年龄较大的患者中哪些适合移植。绝对禁忌症很少，如活动性感染和近期恶性肿瘤，但老年患者有许多相对或潜在禁忌症。在世界范围内，可用于移植的器官是有限的。一些中心不愿在老年接受者中使用扩大标准供体的器官。这导致等待名单很长，许多年长的患者在等待器官时会死亡。至关重要的是，接受肾脏移植的患者将是受益最大的患者，因此正确选择患者和供体器官至关重要。本文介绍了我们的研究小组先前针对和计划进行的研究，重点针对年龄较大的肾移植受者，尤其侧重于生存期，基本免疫抑制，器官选择和健康相关的生活质量。

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