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首页> 外文期刊>American Journal of Epidemiology and Infectious Disease >Feeding Options and Antiretroviral Prophylaxis among Exposed Infants in Bida, North Central Nigeria
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Feeding Options and Antiretroviral Prophylaxis among Exposed Infants in Bida, North Central Nigeria

机译：尼日利亚中北部比达的婴儿的喂养选择和抗逆转录病毒预防

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Background: Breastfeeding is a major health promoting factor in infants and children in developing countries, but the risk of mother-to-child transmission (MTCT) of HIV by this route is challenging traditional and health policies in low resource countries. Aims: The aim of the study is to determine the effect of feeding options and infant antiretroviral prophylaxis on transmission of HIV in Bida North Central Nigeria. Patients and methods: we reviewed a total of Four hundred and fourteen (414) HIV exposed infants whose dried blood spot (DBS) samples were taken for DNA PCR test between May 2011 and July 2013 and whose parents are on antiretroviral therapy and for whom a complete set of records were available. Results: The most prevalent feeding option was mixed feeding 250(60.4%) followed by exclusive breastfeeding 84(20.3%) and exclusive formula feeding 80(19.3%). The HIV transmission rate is higher among mixed feeding 17.6% followed by exclusive breastfeeding 7.1% and exclusive formula feeding 5.0%. HIV transmission rate of 6.0% was observed for infants that were on antiretroviral prophylaxis and 43.6% for infants who were not on antiretroviral prophylaxis. Conclusion: The study shows the benefits of exclusive formula feeding and the intake of antiretroviral prophylaxis in reducing HIV transmission through breastfeeding.
机译：背景：母乳喂养是发展中国家婴儿和儿童健康的主要促进因素，但是通过这种途径传播艾滋病毒的母婴传播风险正在挑战资源贫乏国家的传统和卫生政策。目的：该研究的目的是确定尼日利亚比达北部中部的喂养方式和婴儿抗逆转录病毒药物预防措施对HIV传播的影响。患者和方法：我们回顾了2011年5月至2013年7月之间抽取的414名（414）HIV感染婴儿的干血斑（DBS）样本进行DNA PCR测试，其父母正在接受抗逆转录病毒治疗，提供了完整的记录集。结果：最普遍的喂养方式是混合喂养250（60.4％），然后是纯母乳喂养84（20.3％）和纯配方奶粉喂养80（19.3％）。在混合喂养中，HIV传播率较高，为17.6％，其次是纯母乳喂养7.1％和纯配方奶喂养5.0％。接受抗逆转录病毒预防的婴儿的HIV传播率为6.0％，未接受抗逆转录病毒预防的婴儿的HIV传播率为43.6％。结论：该研究表明，纯母乳喂养和预防摄入抗逆转录病毒药物可减少通过母乳喂养传播的HIV的益处。

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