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Patterns of Antimicrobial therapy in acute tonsillitis: A cross-sectional Hospital-based study from UAE

机译:急性扁桃体炎的抗菌治疗模式:阿联酋基于医院的横断面研究

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Background: Diseases of the ear, nose and throat (ENT) are associated with significant impairment of the daily life and a major cause for absenteeism from work.Aim: The study determined antimicrobial prescription pattern in patients with acute tonsillitis.Materials and Methods: A cross-sectional study was carried out among all the patients attending the ENT department with acute tonsillitis. Data were retrieved from the medical records using a proforma. Statistical analysis was carried out using SPSS.19.Results: Total of 238 patients included (Males 138; females 100). About 96% of total drugs were prescribed by generic name. Median number of drugs prescribed was four (range 1-7). Eighty eight percent of prescriptions contained antimicrobials, (78.5%) analgesics and (57.9%) antipyretics. Amoxicillin / Clavulanic acid (24.8%) and Ceftriaxone (12.2%) were the most commonly prescribed antimicrobials. Parenteral route was preferred in 41.6%. About 23.7% of the patients on Amoxicillin / Clavulanic acid had received the drug as intravenous injection. Culture and sensitivity tests were carried out in 106 (44.5%) of the cases. Antimicrobials were changed / added after the culture and sensitivity test in 25 patients.Conclusion: Study findings highlighted rational practices in drug prescribing. Therapeutic guidelines based on current sensitivity pattern optimize the use of antimicrobial agents.
机译:背景:耳鼻喉疾病(ENT)与日常生活的严重损害和工作中的缺勤有关,目的:该研究确定了急性扁桃体炎患者的抗菌处方类型。材料与方法:A在参加耳鼻喉科的所有急性扁桃体炎患者中进行了横断面研究。使用形式表从医疗记录中检索数据。使用SPSS软件进行统计分析。19。结果:共纳入238例患者(男性138例;女性100例)。约有96%的药物是用通用名称开的。所开具的药物中位数为4(范围1-7)。 88%的处方药中含有抗菌剂,(78.5%)镇痛药和(57.9%)解热药。阿莫西林/克拉维酸(24.8%)和头孢曲松钠(12.2%)是最常用的抗菌药物。胃肠外途径是首选的41.6%。服用阿莫西林/克拉维酸的患者中约有23.7%接受了静脉注射药物。在106例(44.5%)病例中进行了培养和敏感性测试。在对25例患者进行培养和敏感性测试后,更改/添加了抗菌药物。结论:研究结果突出了药物处方的合理做法。基于当前敏感性模式的治疗指南可优化抗菌剂的使用。

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