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首页> 外文期刊>Annals of Maxillofacial Surgery >Evaluation of the different biomaterials used in alveolar cleft defects in children
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Evaluation of the different biomaterials used in alveolar cleft defects in children

机译：评估儿童牙槽裂缺损中使用的不同生物材料

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The aim of this study was to use a literature review to evaluate and compare the different biomaterials used in surgeries for the closure of the palatal and alveolar clefts as alternatives to isolated autografting. For the search strategy, the PubMed and Medline databases were used with the indexing terms “'cleft palate' (Mesh), 'biocompatible materials' (Mesh), and 'dentistry' (Mesh).” There was no restriction on language or publication time. After the research, 26 articles were found, and then, only the filter for clinical trials was selected. With this methodology, five articles were selected. The full texts have been carefully evaluated. The main issue among the five selected articles was the closure of a cleft palate and/or alveolar bone with the use of different types of biomaterials (e.g. autogenous bone from the iliac crest and chin, deproteinized bovine bone (DBB), β-tricalcium phosphate (β-TCP), synthetic resorption based on calcium sulfate, and the engineering of bone tissue); they evaluated preoperative and postoperative clinically and through imaging tests. The autogenous bone associated with DBB or β-TCP significantly reduces the amount of autogenous bone harvested from the iliac crest, morbidity, and the hospitalization of the patient, and the isolated use of bovine hydroxyapatite resulted in lower bone density compared to that from autogenous bone.
机译：这项研究的目的是使用文献综述来评估和比较外科手术中用于闭合pa裂和牙槽裂的不同生物材料，以作为离体自体移植的替代方法。对于搜索策略，PubMed和Medline数据库使用了索引词“'裂”（网格），“生物相容性材料”（网格）和“牙科”（网格）。语言或出版时间没有限制。经过研究，找到26篇文章，然后仅选择用于临床试验的过滤器。通过这种方法，选择了五篇文章。全文已经过仔细评估。在五篇选定的文章中，主要问题是使用不同类型的生物材料（例如from和下巴的自体骨，脱蛋白牛骨（DBB），β-磷酸三钙）封闭a裂和/或牙槽骨（β-TCP），基于硫酸钙的合成吸收和骨组织工程）;他们通过成像检查评估了术前和术后的临床状况。与DBB或β-TCP相关的自体骨显着减少了从the，患者的发病率和住院治疗中获得的自体骨量，并且与自体骨相比，单独使用牛羟基磷灰石导致骨密度降低。

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