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Intersphincteric resection for very low rectal cancer: A review of the updated literature

机译:极低位直肠癌括约肌切除术:最新文献综述

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Abstract Intersphincteric resection (ISR) has rapidly increased worldwide including laparoscopic surgery. However, there are some concerns for the definition of ISR, surgical technique, oncological outcome, anal function, and quality of life (QoL). The aim of the present study is to evaluate those issues. A review of this surgical technique was carried out by searching English language literature of the PubMed online database and appropriate articles were identified. With regard to open-ISR, the morbidity rate ranged from 7.5% to 38.3%, with lower mortality rates. Local recurrence rates varied widely from 0% to 22.7%, with a mean follow-up duration of 40–94?months. Disease-free and overall 5-year survival rates were 68–86% and 76–97%, respectively. Those outcomes were equivalent to laparoscopic-ISR. Surgical and oncological outcomes of ISR were generally acceptable. However, accurate evaluation of anal function and QoL was difficult because of a lack of standard assessment of various patient-related factors. The surgical and oncological outcomes after ISR seem to be acceptable. The ISR technique seems to be valid as an alternative to abdominoperineal resection in selected patients with a very low rectal cancer. However, both necessity for ISR and expectations of QoL impairment as a result of functional disorder should be fully discussed with patients before surgery.
机译:摘要包括腹腔镜手术在内的全球括约肌切除术(ISR)迅速增长。但是,对于ISR的定义,手术技术,肿瘤学结局,肛门功能和生活质量(QoL),存在一些担忧。本研究的目的是评估这些问题。通过检索PubMed在线数据库的英语文献,对该手术技术进行了回顾,并确定了适当的文章。关于开放式ISR,发病率从7.5%到38.3%不等,死亡率较低。局部复发率从0%到22.7%不等,平均随访时间为40-94个月。无病生存期和5年总生存率分别为68-86%和76-97%。这些结果等同于腹腔镜ISR。 ISR的手术和肿瘤治疗结果普遍可以接受。但是,由于缺乏对各种患者相关因素的标准评估,因此难以准确评估肛门功能和生活质量。 ISR后的手术和肿瘤治疗结果似乎可以接受。在极低的直肠癌患者中,ISR技术似乎可以替代腹部手术切除。但是,在手术前应与患者充分讨论ISR的必要性和功能障碍导致的QoL损害的期望。

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