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首页> 外文期刊>American Journal of Sports Science and Medicine >Overestimated Effect of Epo Administration on Aerobic Exercise Capacity: A Meta-Analysis
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Overestimated Effect of Epo Administration on Aerobic Exercise Capacity: A Meta-Analysis

机译：Epo给药对有氧运动能力的过高估计：一项荟萃分析

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Recent studies examining the relationship between epo doping and aerobic performance (the EDAP–relationship) yield conflicting results. To resolve this inconclusiveness in an empirical way, we conducted a meta–analysis on 17 laboratory studies and assessed effect sizes (unbiased d, r and r2) of the epo–induced improvements in aerobic exercise capacity measured by maximal oxygen uptake (VO2max) and maximal aerobic power output (Wmap). The fixed, pooled EDAP effect size estimates were moderate, d = 0.41–0.49, r = .19–.44, and r2 = .04–.19, revealing a shift of approximately half SD in performances of the epo–treated compared to the non–treated participants. As to VO2max, we observed the strongest post test performance (M = 64.39ml kg-1 min-1) in double blind, placebo controlled studies on performances assessed at sea level with an increase from pre to post tests of M = 4.02ml kg-1 min-1. Regarding Wmap, the increase was M = 26W with the strongest post test performance of M = 398W observed in similar studies as VO2max. Percents improvement from pre to post tests varied between M = 6–7% (VO2max), and M = 7–8% (Wmap). The largest improvement in VO2max we found equals an increase in velocity of about 1km/h. Consistent with recent studies criticizing the EDAP-relationship our findings indicate that its strength is overestimated. In turn, this entails that the relationship between epo doping and cyclists’ performances at real contests is overrated too.
机译：最近的研究检查了epo掺杂与有氧运动之间的关系（EDAP关系），产生了矛盾的结果。为了以经验的方式解决这一不确定性，我们对17个实验室研究进行了荟萃分析，并评估了通过最大摄氧量（VO2max）和EPO引起的有氧运动能力的改善（无偏d，r和r2）。最大有氧功率输出（Wmap）。固定的，合并的EDAP效应量估计值适中，d = 0.41–0.49，r = .19–.44，r2 = .04–.19，表明经epo治疗的患者的表现与标准治疗相比大约降低了一半SD。未经治疗的参与者。至于最大摄氧量，我们在双盲，安慰剂对照研究中观察到了最强的测试后性能（M = 64.39ml kg-1 min-1），在海平面上评估了性能，从测试前到测试后M = 4.02ml kg -1分-1。关于Wmap，增加量为M = 26W，在与VO2max相似的研究中观察到的最强的测试后性能为M = 398W。从测试前到测试后的改善百分比介于M = 6–7％（VO2max）和M = 7–8％（Wmap）之间。我们发现最大摄氧量的改善等于速度增加约1 km / h。与最近批评EDAP关系的研究一致，我们的发现表明其强度被高估了。反过来，这也意味着epo兴奋剂与真正比赛中骑车人的表现之间的关系也被高估了。

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