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首页> 外文期刊>American Journal of Sports Science and Medicine >Peak Expiratory Flow Rate – A Consistent Marker of Respiratory Illness Associated with Childhood Obesity
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Peak Expiratory Flow Rate – A Consistent Marker of Respiratory Illness Associated with Childhood Obesity

机译：峰值呼气流速–与儿童肥胖有关的呼吸系统疾病的一致标志

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Childhood obesity is a prevalent global health problem that leads to onset of serious health problems. One of such major health problems is respitarory disorders induced by obesity especially in childhood. Peak expiratory flow rate (PEFR) is a convenient tool for quantitative and qualitative estimation of pulmonary function, which can easily be measured by peak flow meter. Present review has been focused to find out the applicability of PEFR as a marker of childhood obesity induced respiratory complications. Several studies revealed that obesity has strong association with PEFR that was significantly lower in individuals with obesity. Such association was attributed to the increased airway resistance and respiratory muscle dysfunction as a result of excess fat deposition. BMI, a good predictor of obesity also exhibited significant correlated with spirometric variables, e.g., FEV1, FVC, PEFR, etc. Waist to hip ratio has also been found to be an alternative of BMI for prediction of PEFR. Researchers hypothesised that fat accumulation over the chest wall reduces the PEFR mostly among all the pulmonary function indices and negative correlation was observed between pulmonary function parameters and visceral adiposity that in turn establishes that visceral fat deposition negatively affects the pulmonary activities and affects airway hyper responsiveness (AHR) in asthmatic and non-asthmatic children. Evidences further suggest that obesity causes asthma in children. It may further be hypothesized that PEFR is a good marker to diagnose the pulmonary disorders originated as a result of obesity that in turn may be evaluated from BMI or waist to hip ratio.
机译：儿童肥胖是普遍存在的全球性健康问题，导致严重的健康问题发作。这种主要的健康问题之一是肥胖引起的再发性疾病，尤其是在儿童时期。呼气峰值流速（PEFR）是定量和定性评估肺功能的便捷工具，可通过峰值流量计轻松测量。目前的审查重点是找出PEFR作为儿童肥胖引起的呼吸系统并发症的标志物的适用性。几项研究表明，肥胖与PEFR有很强的联系，而肥胖个体的PEFR显着较低。这种关联归因于过量脂肪沉积导致气道阻力增加和呼吸肌功能障碍。良好的肥胖预测指标BMI也显示出与肺活量测定变量（例如FEV1，FVC，PEFR等）显着相关。腰臀比也被发现是BMI预测PEFR的替代方法。研究人员假设，在所有肺功能指标中，胸壁上的脂肪积聚大部分会降低PEFR，并且观察到肺功能参数与内脏脂肪之间存在负相关关系，进而证明内脏脂肪沉积会对肺活动产生负面影响，并影响气道高反应性（哮喘和非哮喘儿童中的AHR）。证据进一步表明，肥胖会导致儿童哮喘。可以进一步假设PEFR是诊断肥胖引起的肺部疾病的良好标志物，进而可以从BMI或腰围与臀围比率进行评估。

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