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The Effects of Two Novel Copper-Based Formulations on Helicobacter pylori

机译：两种新型铜基制剂对幽门螺杆菌的影响

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We investigated the effects of two novel copper-based inorganic formulations for their activity against 60 isolates of Helicobacter pylori (Hp). The two copper-based formulations were tested against three NCTC Helicobacter pylori isolates and 57 clinical strains isolated from the UK and Italy in time-kill assays. Both copper-based formulations were bio-cidal against all Helicobacter pylori strains tested reducing the viable count by 4–5 log within 2 h. These two copper-based anti-microbial agents deserve further study in relation to the treatment of H. pylori-related gastric disease.
机译：我们调查了两种新型铜基无机制剂对60株幽门螺杆菌（Hp）分离物的活性的影响。两种铜基制剂通过时间杀灭法针对从英国和意大利分离出的三种NCTC幽门螺杆菌和57种临床菌株进行了测试。两种铜基制剂均对所有测试的幽门螺杆菌具有杀生物作用，可在2小时内将存活计数降低4-5 log。这两种铜基抗菌剂在幽门螺杆菌相关胃病的治疗方面值得进一步研究。

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