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Understanding Antibiotic Use in Minya District, Egypt: Physician and Pharmacist Prescribing and the Factors Influencing Their Practices

机译:了解埃及民雅区的抗生素使用:医师和药剂师开药处方及其影响因素

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Overuse of antibiotics has contributed to the emergence of antibiotic-resistant bacteria globally. In Egypt, patients can purchase antibiotics without a prescription, and we hypothesized frequent inappropriate antibiotic prescribing and dispensing. We interviewed physicians (n = 236) and pharmacists (n = 483) and conducted focus groups in Minya, Egypt, to assess attitudes and practices regarding antibiotic prescribing for outpatient acute respiratory infections (ARI). Antibiotics were reportedly prescribed most of the time or sometimes for colds by 150 (64%) physicians and 326 (81%) pharmacists. The most commonly prescribed antibiotics were β-lactams. Macrolides were the second most commonly prescribed for colds and sinusitis. The prescription of more than one antibiotic to treat pneumonia was reported by 85% of physicians. Most respondents thought antibiotic overuse contributes to resistance and reported “patient self-medication” as the biggest driver of overuse. Fifty physicians (21%) reported that they had prescribed antibiotics unnecessarily, citing patient over-the-counter access as the reason. Physicians 40 years of age and those who treat adults were more likely to prescribe antibiotics for colds. Overall, we found a high rate of unwarranted outpatient antibiotic prescribing and dispensing for ARIs. Patient access to OTC antibiotics contributes to over-prescribing. National guidelines for ARI treatment, provider education and national policy requiring a physician’s prescription for antibiotics may improve appropriate antibiotic use in Egypt.
机译:过度使用抗生素已导致全球耐药菌的出现。在埃及,患者无需处方即可购买抗生素,我们假设经常不适当地开处方和分配抗生素。我们采访了埃及的Minya的医师(n = 236)和药剂师(n = 483),并进行了焦点小组讨论,以评估关于抗生素处方用于门诊急性呼吸道感染(ARI)的态度和做法。据报道,大部分时间(有时是150名(64%))医生和326名(81%)药剂师开了抗生素处方药。最常用的抗生素是β-内酰胺类。大环内酯类药物是第二种最常用于感冒和鼻窦炎的药物。 85%的医生报告了一种以上的抗生素治疗肺炎的处方。大多数受访者认为抗生素过度使用会导致耐药性,并报告“患者自我用药”是过度使用抗生素的最大驱动力。五十位医师(21%)报告说,他们不必要地开出了抗生素处方,理由是患者可以通过非处方途径获得。 <40岁以下的医师和治疗成人的医师更有可能开抗生素预防感冒。总体而言,我们发现大量不需要的门诊抗生素处方和配药用于ARI。患者使用非处方药会导致处方过量。有关ARI治疗的国家指南,提供者教育和要求医生开具抗生素处方的国家政策,可能会改善埃及的适当抗生素使用情况。

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