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Antibiotic Stewardship Initiatives as Part of the UK 5-Year Antimicrobial Resistance Strategy

机译：作为英国5年抗菌素耐药性策略的一部分，开展了抗生素管理计划

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摘要

Antibiotic use is a major driver for the emergence and spread of antibiotic resistance. Antimicrobial stewardship programmes aim to improve antibiotic prescribing with the objectives of optimizing clinical outcomes while at the same time minimizing unintended consequences such as adverse effects and the selection of antibiotic resistance. In 2013, a five-year national strategy for tackling antimicrobial resistance was published in the UK. The overarching goal of the strategy is to slow the development and spread of resistance and to this end it has three strategic aims, namely to improve knowledge and understanding of resistance, to conserve and steward the effectiveness of existing treatments and to stimulate the development of new antibiotics, diagnostics and novel therapies. This article reviews the antimicrobial stewardship activities included in the strategy and describes their implementation and evaluation.
机译：抗生素的使用是产生和传播抗生素耐药性的主要驱动力。抗菌素管理计划旨在改善抗生素处方，以优化临床结果为目标，同时将不良后果（如不良反应和抗生素耐药性的选择）降至最低。 2013年，英国发布了一项解决抗菌素耐药性的五年国家战略。该战略的总体目标是减缓抗药性的发展和扩散，为此，它具有三个战略目标，即增进对抗药性的认识和了解，保护和指导现有疗法的有效性以及刺激新抗药性的发展抗生素，诊断学和新型疗法。本文回顾了该策略中包括的抗菌管理活动，并描述了其实施和评估。

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