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Biogenic synthesis of silver nanoparticles and their antioxidant and antibacterial activity

机译:银纳米粒子的生物合成及其抗氧化和抗菌活性

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摘要

Nanomedicine utilizes biocompatible nanomaterials for diagnostic and therapeutic purposes. The present study reports the use of Helicteres isora root extract for the synthesis of silver nanoparticles (AgNPs). The synthesized AgNPs were initially noticed through visual color change from yellow to reddish brown and further confirmed by surface plasmonic resonance (SPR) band at 450?nm using UV–visible spectroscopy. Morphology and size of AgNPs were determined by transmission electron microscopy (TEM) analysis. X-ray diffraction (XRD) study revealed crystalline nature of AgNPs. The prolonged stability of AgNPs was due to capping of oxidized polyphenols and carboxyl protein which was established by Fourier transform infrared spectroscopy (FTIR) study. In addition, the synthesized AgNPs were tested for antioxidant and antibacterial activities. It showed good antioxidant activity as compared to butylated hydroxytoluene (BHT) and ascorbic acid as standard antioxidant. It could be concluded that H. isora root extract can be used efficiently in the production of potential antioxidant and antibacterial AgNPs for commercial application.
机译:纳米医学利用生物相容性纳米材料进行诊断和治疗。本研究报告使用Helicteres isora根提取物合成银纳米颗粒(AgNPs)。最初通过从黄色到红棕色的视觉颜色变化注意到合成的AgNPs,并通过使用UV-可见光谱在450?nm的表面等离子体共振(SPR)谱带进一步确认。 AgNPs的形态和大小通过透射电子显微镜(TEM)分析确定。 X射线衍射(XRD)研究揭示了AgNPs的晶体性质。 AgNPs的长期稳定性归因于氧化多酚和羧基蛋白的封端,这是通过傅立叶变换红外光谱(FTIR)研究确定的。此外,测试了合成的AgNPs的抗氧化和抗菌活性。与丁基化羟基甲苯(BHT)和抗坏血酸作为标准抗氧化剂相比,它具有良好的抗氧化剂活性。可以得出的结论是,鸢尾根提取物可以有效地用于商业用途的潜在抗氧化剂和抗菌AgNP的生产中。

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