Modelling of the mechanical behaviour of porcine carotid artery undergoing inflation-deflation test

Jan Vychytil; Fanny Moravec; Petra Kochová; Jitka Kuncová; Jitka ?víglerová

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Modelling of the mechanical behaviour of porcine carotid artery undergoing inflation-deflation test

机译：猪颈动脉进行充气-放气试验的力学行为建模

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Samples of porcine carotid artery are examined using Tissue bath MAYFLOWER, Perfusion of tubular organs Version, Type 813/6. Pressure-diameter diagrams are obtained for fixed axial extension and volumetric flow rate. Finite element analysis of the experiment, performed using COMSOL software, indicates a negligible effect of given flow rate on the mechanical response of the tested sample. Also the effect of clamped ends is shown to be local only. Hence, static analysis in MATLAB software is performed considering the arterial segment as an incompressible hyperelastic axisymmetric tube. Residual stress at the load-free configuration is taken into account resulting in the overall stiffening of the model. Comparison of theoretical and experimental pressure-diameter curves results in the identification of material parameters using the least square method. In addition to classical hyperelastic models, such as the neo-Hookean and the Fung’s exponential, two-scale model mimicking arrangement of soft tissue is considered.

机译：使用组织浴MAYFLOWER（灌注小管器官版本813/6型）检查猪颈动脉样本。获得固定轴向延伸量和体积流量的压力-直径图。使用COMSOL软件进行的实验有限元分析表明，给定流速对被测样品的机械响应的影响可忽略不计。夹紧端的作用也仅显示为局部的。因此，在MATLAB软件中进行静态分析时将动脉段视为不可压缩的超弹性轴对称管。考虑了无负载配置下的残余应力，从而导致模型整体硬化。理论和实验压力-直径曲线的比较导致使用最小二乘法确定材料参数。除了经典的超弹性模型（例如新Hookean和Fung的指数模型）外，还考虑了模仿软组织排列的两尺度模型。

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《Applied and Computational Mechanics》 |2010年第2期|共页
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Jan Vychytil; Fanny Moravec; Petra Kochová; Jitka Kuncová; Jitka ?víglerová;
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中图分类计算技术、计算机技术;
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Modelling of the mechanical behaviour of porcine carotid artery undergoing inflation-deflation test

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