...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Archives of Biological Sciences >INCREASED TUMOR NECROSIS FACTOR ALPHA AND INTERLEUKIN-6 SERUM LEVELS AND THEIR CORRELATION WITH LABORATORY PARAMETERS IN PATIENTS WITH IMPORTED MALARIA
【24h】

INCREASED TUMOR NECROSIS FACTOR ALPHA AND INTERLEUKIN-6 SERUM LEVELS AND THEIR CORRELATION WITH LABORATORY PARAMETERS IN PATIENTS WITH IMPORTED MALARIA

机译：进口疟疾患者的肿瘤坏死因子α和白细胞介素-6水平升高及其与实验室参数的相关性

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

In malaria, blood concentrations of proinflammatory cytokines, such as tumor necrosis factor alpha (TNF-α) and interleukin (IL)-6, are increased. In a study which included 34 patients, TNF-α and IL-6 were examined in two phases, immediately after the admission of patients, and at the end of antimalarial therapy, when the parasitemia was negative. The results show a significant increase of TNF-α and IL-6 in the first phase, before the effects of antimalarial therapy. A very strong correlation between TNF-α and IL-6 is also confirmed, which suggests their coordinated production. Increased TNF-α values were correlated with an older age, the level of parasitemia, the number of platelets and leukocytes, elevated values of procalcitonin, D-dimer and lactate dehydrogenasе, and lower values of serum iron and antithrombin. Increased values of IL-6 were correlated with the level of parasitemia, the number of platelets and leukocytes, and elevated values of D-dimer and lactates.
机译：在疟疾中，促炎细胞因子（例如肿瘤坏死因子α（TNF-α）和白介素（IL）-6）的血液浓度增加。在一项包括34名患者的研究中，入院后立即和寄生虫阴性时抗疟疾治疗结束时分两个阶段检查TNF-α和IL-6。结果表明，在抗疟疾治疗生效之前的第一阶段，TNF-α和IL-6显着增加。还证实了TNF-α和IL-6之间非常强的相关性，这表明它们是协调产生的。 TNF-α值升高与年龄，寄生虫血症水平，血小板和白细胞数量，降钙素原，D-二聚体和乳酸脱氢酶升高以及血清铁和抗凝血酶降低有关。 IL-6值升高与寄生虫病水平，血小板和白细胞数量以及D-二聚体和乳酸的升高有关。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号