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首页> 外文期刊>Archives of disease in childhood >P86?Treatment modalities in peripheral facial nerve palsy in children and adolescents
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P86?Treatment modalities in peripheral facial nerve palsy in children and adolescents

机译：P86？儿童和青少年周围性面神经麻痹的治疗方式

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Background Bell′s palsy is the most common type of peripheral facial palsy in pediatrics. Recent studies strongly support the combined therapy with corticosteroids (CS), antiviral drugs and vitamins B. Our study aims to assess the effectiveness of proposed therapeutic modalities, including the relation between the patients‘ recovery and their age, etiological factors and applied treatment. Methods The retrospective analysis involved 88 patients (52 females/36 males), between 18 months and 18 years old; the average age was 11.7 years. Data was obtained from the documentation of patients hospitalized at the Clinic of Neurology and Psychiatry for Children and Youth in Belgrade, from 2000 to 2017. House Brackmann′s scale was used for the assessment of disease course and outcome. Pearson′s χ2 test, Friedman′s test and general linear model were applied for statistical data processing. Results The majority of patients were treated with combined CS/vitamins (42.0%) and CS/antiviral/vitamins (17.0%), whereas CS only received 22.7% of patients, all with an appropriate physical treatment. The group of idiopathic paralysis makes 62.5%, while the incidence of symptomatic paralysis is 37.5%; however, the recovery rate between these groups has not been shown (p=0.309). Patients received CS therapy were divided into 4 groups: CS only, CS+antiviral, CS+vitamins B, and CS+antiviral+vitamins B. The statistically significant recovery was registered in each group (p 0.001); however, no difference was found between the groups in term of recovery rate (p=865). For the assessment of recovery period in relation to the age, the obtained p value was 0.054, a borderline level, suggesting a faster recovery of children at younger age. Conclusion The acute one-sided mimic musculature weakness is mostly idiopathic. The effectiveness of the CS therapy was strongly supported, suggesting CS as a core treatment for the Bell′s palsy.
机译：背景贝尔氏麻痹是儿科患者最常见的周围性面部麻痹。最近的研究强烈支持将皮质类固醇（CS），抗病毒药和维生素B联合治疗。我们的研究旨在评估提议的治疗方式的有效性，包括患者康复与年龄，病因和应用治疗之间的关系。方法回顾性分析88例患者，其中女性52例，男性36例，年龄18个月至18岁。平均年龄为11.7岁。数据来自2000年至2017年在贝尔格莱德的儿童和青少年神经病学和精神病学诊所住院的患者的文献。HouseBrackmann's量表用于评估病程和结局。采用皮尔逊氏χ2检验，弗里德曼检验和一般线性模型进行统计数据处理。结果大多数患者接受了CS /维生素（42.0％）和CS /抗病毒/维生素（17.0％）的联合治疗，而CS仅接受22.7％的患者，均接受了适当的物理治疗。特发性麻痹组占62.5％，而症状性麻痹的发生率为37.5％。但是，这些组之间的恢复率尚未显示（p = 0.309）。接受CS治疗的患者分为4组：仅CS，CS +抗病毒，CS +维生素B和CS +抗病毒+维生素B。每组均具有统计学显着性恢复（p <0.001）。然而，两组之间的恢复率没有差异（p = 865）。为了评估与年龄有关的恢复期，获得的p值为0.054，这是一个临界水平，表明年龄较小的儿童恢复得更快。结论急性单侧模仿性肌肉组织无力多数是特发性的。强烈支持CS治疗的有效性，这表明CS是贝尔麻痹的核心治疗方法。

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