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首页> 外文期刊>Asian journal of animal and veterinary advances >Surgical and Histopathological Evaluation of Suture Materials for Closure of Colonic Wounds after Experimental Typhlectomy in Dogs
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Surgical and Histopathological Evaluation of Suture Materials for Closure of Colonic Wounds after Experimental Typhlectomy in Dogs

机译：实验性膝关节切除术在犬中闭合结肠伤口的缝合材料的手术和组织病理学评估

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Typhlectomy has been prescribed for the treatment of cecal affections in dogs. The effect of suture materials on healing process after typhlectomy has not been studied yet. Twenty seven Mongrel dogs were randomly divided into 3 groups. Chromic catgut, silk and vicryl were used for groups 1, 2 and 3, respectively and 3 dogs each were euthanized on the 7th, 14th and 21st POD for evaluation of the healing process of colonic wounds. None of the animals had post-operative abnormal clinical signs. Non-significant differences in the mean height of the ridges were observed among the 3 groups. Groups 1 and 2 showed a moderate to severe mucosal necrosis at free part of inverted colonic edges, minimal cellular infiltration in lamina properia, inflammatory cell infiltration in tunica muscularis and moderate to severe tissue reaction around the suture material whereas, group 3 exhibited least mucosa necrosis, minimal destruction of tunica muscularis and low inflammatory cell reaction around suture material. Scores of these lesions did not differed significantly among the 3 groups but tissue reaction around the suture material differed significantly (p<0.05). In conclusion, vicryl was the most convenient and superior suture material for colonic wound healing after typhlectomy in dogs.
机译：业已开出伤寒切除术，以治疗犬的盲肠病。尚未研究缝合材料对伤寒切除术后愈合过程的影响。将27只杂种犬随机分为3组。第1、2和3组分别使用铬肠线，丝线和vicryl线，并且在第7、14和21日POD处分别对3只狗实施安乐死，以评估结肠伤口的愈合过程。没有动物具有术后异常的临床体征。 3组之间的平均脊高没有显着差异。第1组和第2组在倒结肠边缘的自由部分出现中度至重度粘膜坏死，固有层的细胞浸润最小，肌膜炎性细胞浸润以及缝合材料周围的中度至重度组织反应，而第3组的黏膜坏死最少，最小的肌膜破坏和缝合材料周围的低炎症细胞反应。这些损伤的评分在三组之间没有显着差异，但是缝合材料周围的组织反应差异显着（p <0.05）。综上所述，vicryl是犬类羊膜切除术后结肠伤口愈合的最方便，最优质的缝合材料。

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