• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Artificial cells, blood substitutes, and immobilization biotechnology. >Microencapsulated Saccharomyces cerevisiae Column Bioreactor for Potential Use in Renal Failure Uremia
【24h】

Microencapsulated Saccharomyces cerevisiae Column Bioreactor for Potential Use in Renal Failure Uremia

机译：微囊化啤酒酵母柱生物反应器在肾衰竭尿毒症中的潜在用途

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

A novel bioreactor containing viable APA microencapsulated yeast cells was designed. Rat plasma was used for perfusion. Yeast cell loading and perfusion flow rate were studied to maximize urea removal. An increase in column loading from 25% to 100%, increased urea removal from 5.67 ± 1.34% to 30.45 ± 0.48%. An increase in flow rate from low to high, increased urea removal from 30.46% to 40.4%. At 100% column loading and high flow rate, the creatinine and phosphate concentrations decreased by 22% and 10%, respectively, while ammonia concentrations increased by 58.9% (p 0.05). Our in-vitro perfusion study demonstrates that microencapsulated yeast cells can remove urea efficiently.
机译：设计了一种新型的生物反应器，其中含有活的APA微囊化酵母细胞。大鼠血浆用于灌注。为了最大程度地去除尿素，研究了酵母细胞的负载和灌注流速。色谱柱上样量从25％增加到100％，尿素去除率从5.67±1.34％增加到30.45±0.48％。流速从低到高增加，尿素去除率从30.46％增加到40.4％。在100％的色谱柱上样量和高流速下，肌酐和磷酸盐浓度分别降低了22％和10％，而氨气浓度则提高了58.9％（p <0.05）。我们的体外灌注研究表明，微囊化酵母细胞可以有效去除尿素。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号