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首页> 外文期刊>Artificial cells, blood substitutes, and immobilization biotechnology. >Preparation and the Influencing Factors of Cetirizine Hydrochloride Microemulsion
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Preparation and the Influencing Factors of Cetirizine Hydrochloride Microemulsion

机译：盐酸西替利嗪微乳的制备及影响因素

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: We constructed pseudo-ternary phase diagrams to obtain the area of water-in-oil (w/o) microemulsion formation, prepared cetirizine hydrochloride microemulsion, and evaluated its quality. The w/o microemulsion had been formulated using span80 as surfactant, alcohol as co-surfactant, and oleinic acid as oil. Pseudo-ternary phase diagrams were constructed to evaluate the phase behavior of the w/o microemulsion. The properties, including appearance, particle size, and stability, were determined. The stable w/o microemulsion could be prepared using span80/ alcohol/ oleinic acid/ water (1.2/ 4.8/ 2/ 2). The w/o microemulsion is a new carrier for hydrosoluble drugs, which are easy to prepare with consistent quality.
机译：：我们构建了伪三元相图，以获得油包水（w / o）微乳液形成的面积，制备了西替利嗪盐酸盐微乳液，并评估了其质量。使用span80作为表面活性剂，醇作为助表面活性剂和油酸作为油来配制w / o微乳液。构建伪三元相图以评估w / o微乳液的相态。确定了包括外观，粒度和稳定性的性质。可以使用span80 /酒精/油酸/水（1.2 / 4.8 / 2/2）制备稳定的无水微乳液。 w / o微乳液是水溶性药物的新载体，水溶性药物易于制备且质量稳定。

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