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首页> 外文期刊>Asian journal of surgery >Efficacy and complications of 125I seeds combined with percutaneous vertebroplasty for metastatic spinal tumors: A literature review
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Efficacy and complications of 125I seeds combined with percutaneous vertebroplasty for metastatic spinal tumors: A literature review

机译： 125 I种子联合经皮椎体成形术治疗转移性脊柱肿瘤的疗效和并发症：文献综述

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摘要

To review the efficacy and complications of125I seeds combined with percutaneous vertebroplasty for the treatment of metastatic spinal tumors. We searched PubMed/MEDLINE from its inception to November 2018 for articles on metastatic spinal tumors treated with125I seeds combined with percutaneous vertebroplasty. A total of 273 articles were identified in PubMed/MEDLINE based on the search criteria. After deleting duplicate articles including two retrospective studies and three case control studies, five studies were included in this systematic review. In total, 161 patients aged from 49.2 to 62 years were included. The operative levels consisted of the thoracic vertebrae and lumbar vertebrae. Bone cement leakage occurred in 7 cases. None of the patients developed radiation myelopathy. Percutaneous vertebroplasty plus125I seeds implantation is an effective palliative treatment and can alleviate back pain and enhance vertebral body strength in patients with end-stage spinal metastatic tumors. In future research, the effective dosage of125I seeds implantation, the anchoring of seeds with safe distance, and the bone cement distribution in the vertebral body will be next research hotspot.
机译：综述125I种子联合经皮椎体成形术治疗转移性脊柱肿瘤的疗效和并发症。我们从PubMed / MEDLINE成立至2018年11月期间搜索了用125I种子联合经皮椎体成形术治疗的转移性脊柱肿瘤的文章。根据搜索标准，在PubMed / MEDLINE中总共鉴定出273条文章。在删除重复的文章（包括两项回顾性研究和三项病例对照研究）之后，这项系统评价包括五项研究。总共纳入161位年龄在49.2至62岁之间的患者。手术水平包括胸椎和腰椎。发生骨水泥渗漏7例。所有患者均未发生放射性脊髓病。经皮椎体成形术加125 I种子植入是一种有效的姑息治疗，可减轻晚期脊柱转移性肿瘤患者的背痛并增强椎体强度。在未来的研究中，125 I种子植入的有效剂量，安全距离的种子锚固以及椎骨中骨水泥的分布将是下一个研究热点。

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