...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Annals of Indian Academy of Neurology >A pilot study on utility of Malayalam version of Addenbrooke's Cognitive Examination in detection of amnestic mild cognitive impairment: A critical insight into utility of learning and recall measures
【24h】

A pilot study on utility of Malayalam version of Addenbrooke's Cognitive Examination in detection of amnestic mild cognitive impairment: A critical insight into utility of learning and recall measures

机译：马拉雅拉姆语版的阿登布鲁克认知考试在检测轻度轻度认知障碍中的效用的初步研究：对学习和回忆措施的实用性的重要见解

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Aims: This pilot study sought to determine whether the Malayalam adaptation of Addenbrooke's Cognitive Examination (M-ACE) can effectively identify patients with amnestic mild cognitive impairment (a-MCI) and the impact of measures of learning and free recall. Materials and Methods: A cohort of 23 patients with a-MCI aged between 55-80 years diagnosed as per current criteria and 23 group matched cognitively normal healthy controls (CNHC) were studied. The measures of acquisition and delayed recall were the Rey Auditory Verbal Learning Test (RAVLT) and Wechsler Memory Scale (WMS)-III (verbal and visual subsets) and Delayed Matching-to-sample Test (DMS)-48. Test scores of M-ACE registration and recall scores were included. To examine the differences in test performances between the groups, we compared the number of subjects with test scores less than 1.5 standard deviation (SD) of the control scores. Comparisons between a-MCI and controls were drawn using Fisher's exact test and Mann-Whitney U tests. Results: M-ACE registration component ascertained on a 24-point scale failed to demonstrate any differences between a-MCI and controls ( P = 0.665) as opposed to recall judged on a cumulative 10-point scale ( P = 0.001). Significant differences were noted in RAVLT list learning ( P < 0.001) and list recall ( P = 0.003), WMS-III paragraph learning ( P <0.001) and recall ( P = 0.007), visual learning ( P = 0.004) and recall ( P = 0.001). Conclusions: M-ACE recall scores are an effective screening tool to identify patients with suspected a-MCI. Both word list and paragraph learning and recall components have been found to be sensitive to concretely identify a-MCI and impairment on at least 2 tests should be considered in the diagnostic criteria of MCI rather than rely on a single screening battery.
机译：目的：这项初步研究旨在确定马拉雅拉姆语对阿登布鲁克认知考试（M-ACE）的适应性能否有效地识别轻度轻度认知障碍（a-MCI）的患者以及学习和免费回忆措施的影响。资料与方法：研究对象是根据现行标准诊断的23例55-80岁之间的a-MCI患者和23个匹配认知正常健康对照（CNHC）的队列。习得和延迟回忆的方法是雷伊听觉语言学习测验（RAVLT）和韦氏记忆量表（WMS）-III（语言和视觉子集）和延迟匹配样本测验（DMS）-48。包括M-ACE注册测验分数和召回分数。为了检验两组之间测试表现的差异，我们比较了测试分数小于对照分数的1.5标准偏差（SD）的受试者人数。使用Fisher精确检验和Mann-Whitney U检验对a-MCI和对照进行比较。结果：以24点量表确定的M-ACE注册成分未能证明a-MCI与对照之间的任何差异（P = 0.665），与以累积10点量表判断的召回率相反（P = 0.001）。在RAVLT列表学习（P <0.001）和列表回忆（P = 0.003），WMS-III段落学习（P <0.001）和回忆（P = 0.007），视觉学习（P = 0.004）和回忆（ P = 0.001）。结论：M-ACE回忆评分是一种有效的筛查工具，可用于识别疑似a-MCI的患者。已发现单词列表和段落学习与回想组件都对具体识别a-MCI敏感，并且在MCI的诊断标准中应考虑至少2次测试的障碍，而不是依靠单个筛选电池。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号