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首页> 外文期刊>Archivio Italiano di Urologia e Andrologia >A combination of tryptophan, Satureja montana, Tribulus terrestris, Phyllanthus emblica extracts is able to improve sexual quality of life in patient with premature ejaculation
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A combination of tryptophan, Satureja montana, Tribulus terrestris, Phyllanthus emblica extracts is able to improve sexual quality of life in patient with premature ejaculation

机译：色氨酸，Satureja montana，Tri藜，余甘子提取物的组合能够改善早泄患者的性生活质量

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Objective: The management of patient affected by premature ejaculation (PE) is nowadays not highly satisfactory. Here, we aimed to evaluate the tolerability and efficacy of a combination of tryptophan, Satureja montana, Tribulus terrestris, Phyllanthus emblica extracts in order to improve sexual quality of life in patients with premature ejaculation. Materials and methods: All patients attending to 5 urological centers from January 2015 to March 2015, due to premature ejaculation were enrolled in this study. At the enrolment visit, all subjects underwent self-administered IIEF-5, Male Sexual Health Questionnaire-Ejaculation Disorder (MSHQEjD), PEDT and IELTS (calculated as mean from that perceived by partner and that perceived by patient) and underwent urological visit and laboratory examinations. All patients received one tablet per day of a combination of tryptophan, Satureja montana, Tribulus terrestris, Phyllanthus emblica extracts for 3 months (Group A). After 3 months all patients underwent follow-up visit with the same investigations that have been carried out in the enrolment visit. The results were compared with a cohort of patients enrolled in the same period in another urological center and considered as a control group (Group B). All patients in the control group underwent counseling and sexual behavioral treatment without any pharmacological compound. Results: At the follow-up analysis, significant changes in terms of IELT in the Group A (mean difference: 31.90; p < 0.05) at 3 months and versus Group B at the intergroup analysis (mean difference: 30.30; p < 0.05) were reported. In the group A, significant differences from baseline to last follow- up were observed relative to IIEF-5 (mean difference: 1.04; p < 0.05), PEDT (mean difference: -2.57; p < 0.05) and FSH (mean difference: -16.46; p < 0.05). Conclusion: In conclusion, patients affected by PE may significantly benefit from oral therapy with a combination of tryptophan, Satureja montana, Tribulus terrestris, Phyllanthus emblica extracts in terms of IELT and PEDT scores improvement.
机译：目的：如今，对早泄（PE）影响的患者的治疗并不十分令人满意。在这里，我们旨在评估色氨酸，Satureja montana，Tri藜，余甘子提取物的组合的耐受性和功效，以改善早泄患者的性生活质量。资料和方法：本研究纳入了2015年1月至2015年3月因早泄而在5个泌尿科就诊的所有患者。在入组访视时，所有受试者均接受自我管理的IIEF-5，男性性健康问卷-射精障碍（MSHQEjD），PEDT和IELTS（根据伴侣和患者的均值计算），并进行了泌尿科访问和实验室检查考试。所有患者每天服用一粒色氨酸，山茱ature，Tri藜，余甘子提取物的组合，共3个月（A组）。 3个月后，所有患者均接受随访，其随访与入组随访相同。将结果与同期在另一个泌尿外科中心就诊的一组患者进行比较，并视为对照组（B组）。对照组中的所有患者均接受了咨询和性行为治疗，未使用任何药理化合物。结果：在随访分析中，A组在3个月时的IELT发生了显着变化（平均差异：31.90; p <0.05），而在组间分析中，B组的IELT则显着变化（平均差异：30.30; p <0.05）被报道。在A组中，相对于IIEF-5（均值：1.04; p <0.05），PEDT（均值：-2.57; p <0.05）和FSH（均值： -16.46; p <0.05）。结论：总之，就色氨酸，Satureja montana，Tri藜，余甘子提取物的组合改善IELT和PEDT评分而言，受PE影响的患者可能会从口服治疗中显着受益。

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