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首页> 外文期刊>Australasian Medical Journal >The combination of letrozole and metformin has a better therapeutic effect on uterine and ovarian arteries in PCOS patients
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The combination of letrozole and metformin has a better therapeutic effect on uterine and ovarian arteries in PCOS patients

机译：来曲唑和二甲双胍联合使用对PCOS患者的子宫和卵巢动脉有更好的治疗作用

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Background Polycystic ovary syndrome (PCOS) is the most prevalence endocrine disorder in the reproductive age of women. In these patients, medications such as clomiphene citrate, letrozole and metformin are used to induce ovulation and overcome infertility. Aims This study was done for comparing the findings of Color Doppler sonography of the uterine and ovarian arteries in women with PCOS under treatment of two drug groups of letrozole-metformin and clomiphene-metformin. Methods Intervention-applied study was performed on 108 women with secondary infertility due to PCOS in Imam Reza Hospital of Kermanshah in 2016. Women were divided in two groups of 54 people, for investigating the effect of letrozole-metformin and clomiphene-metformin on ovarian and uterine arteries. Results Blood flow in the uterus and ovaries significantly increased after treatment with letrozole-metformin and clomiphene-metformin (P Conclusion Letrozole-metformin as well as clomiphene-metformin have a significant effect on blood flow in the uterus and ovaries. The group which received letrozole-metformin had a better response in this regard.
机译：背景技术多囊卵巢综合征（PCOS）是女性生殖年龄段最常见的内分泌疾病。在这些患者中，使用柠檬酸克罗米芬，来曲唑和二甲双胍等药物诱导排卵并克服不孕症。目的本研究旨在比较接受来曲唑-二甲双胍和克罗米芬-二甲双胍两种药物治疗的多囊卵巢综合征妇女子宫和卵巢动脉的彩色多普勒超声检查结果。方法于2016年在克尔曼沙的伊玛目利萨医院对108例因PCOS继发性不孕的妇女进行干预研究。将妇女分为两组，每组54人，研究来曲唑-二甲双胍和克罗米芬-二甲双胍对卵巢和卵巢癌的影响。子宫动脉。结果用来曲唑-二甲双胍和克罗米芬-二甲双胍治疗后，子宫和卵巢的血流量显着增加（P结论来曲唑-二甲双胍和克罗米芬-二甲双胍对子宫和卵巢的血流都有显着影响。 -二甲双胍在这方面有较好的反应。

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