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Screening Tests of Reproductive Immunology in Systemic Lupus Erythematosus

机译：系统性红斑狼疮生殖免疫学的筛选试验

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Female patients in reproductive age with systemic lupus erythematosus and fertility complications together are observed by rheumatologists, gynecologists, and reproductive immunologists. The paper notes the presence of autoantibodies to zona pellucida, to phospholipids (phosphatidyl serine, phosphatidyl ethanolamine, phosphatidyl inositol, phosphatidyl glycerol, phosphatidic acid, annexin V, beta-2 glycoprotein I, and cardiolipin) and of isoantibodies to sperm cells. Isoantibodies to sperm cells are not significantly predominant, but autoimmunity is well expressed in IgG positivity against phosphatidyl inositol, phosphatidyl ethanolamine, phosphatidyl serine, cardiolipin, and beta-2 glycoprotein I, as well as antizona pellucida antibodies in IgG isotype. According to the levels of autoantibodies we have to choose preventive treatment to protect mother and her foetus.
机译：风湿病学家，妇科医生和生殖免疫学家共同观察到育龄女性患有系统性红斑狼疮和生育并发症。该论文指出存在针对透明带，磷脂（磷脂酰丝氨酸，磷脂酰乙醇胺，磷脂酰肌醇，磷脂酰甘油，磷脂酸，膜联蛋白V，β-2糖蛋白I和心磷脂）的自身抗体以及针对精子细胞的自身抗体。精子细胞的同种抗体并不明显占优势，但是在针对磷脂酰肌醇，磷脂酰乙醇胺，磷脂酰丝氨酸，心磷脂和β-2糖蛋白I以及IgG同种型抗透明带白蛋白抗体的IgG阳性中，自身免疫已很好地表达。根据自身抗体的水平，我们必须选择预防性治疗以保护母亲及其胎儿。

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