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首页> 外文期刊>Autoimmune diseases >Linkage of Multiple Sclerosis and Guillain-Barre Syndrome: A Population-Based Survey in Isfahan, Iran
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Linkage of Multiple Sclerosis and Guillain-Barre Syndrome: A Population-Based Survey in Isfahan, Iran

机译：多发性硬化症与格林巴利综合征的联系：伊朗伊斯法罕的基于人口的调查

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Background. Multiple Sclerosis (MS) and Guillain Barre Syndrome (GBS) are autoimmune demyelinating disorders of Central and Peripheral Nervous system, respectively. The coexistence of these two syndromes in an individual's life span is rare.Objectives. To inspect throughout Isfahan MS society (IMSS) records for MS cases who had history of documented GBS whether before the onset of MS or after it.Methods. This retrospective survey was carried out by analyzing the clinical records of 3,522 MS patients who were registered with IMSS, from April 2003 to July 2010. Eligible cases were requested to attend to IMSS for final clinical/paraclinical examinations.Results. Among 3,522 (2,716 women and 806 men) MS subjects, we could identify seven patients (six females and one male) with documented diagnosis of GBS. Six patients (five women and one man) had developed MS within6.5±7.0(range: 1–16) years after being diagnosed with GBS and one (a woman) had developed GBS three years after the diagnosis of MS.Conclusion. It seems that the development of MS in individuals with history of GBS is more than a simple incidental event.
机译：背景。多发性硬化症（MS）和格林巴利综合症（GBS）分别是中枢和周围神经系统的自身免疫性脱髓鞘疾病。这两种综合症在一个人的一生中并存是罕见的。在整个伊斯法罕MS协会（IMSS）记录中检查是否有MSS发作之前或之后有GBS记录的MS病例。这项回顾性调查是通过分析2003年4月至2010年7月在IMSS登记的3,522名MS患者的临床记录而进行的。要求符合条件的病例参加IMSS进行最终的临床/亚临床检查。在3,522名（2,716名女性和806名男性）MS受试者中，我们可以确定7例具有GBS诊断的患者（6名女性和1名男性）。 6例患者（5名女性和1名男性）在被诊断为GBS后的6.5±7.0（范围：1-16）年内发展为MS，1名（女性）在MS诊断的三年后发展为GBS。在具有GBS病史的个体中，MS的发展似乎不仅仅是一个偶然的事件。

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