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首页> 外文期刊>Arquivos brasileiros de cardiologia. >Reduction in left ventricular hypertrophy in hypertensive patients treated with enalapril, losartan or the combination of enalapril and losartan
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Reduction in left ventricular hypertrophy in hypertensive patients treated with enalapril, losartan or the combination of enalapril and losartan

机译：依那普利，氯沙坦或依那普利和氯沙坦联用治疗的高血压患者左室肥厚的减轻

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OBJECTIVE: To compare the regression of left ventricular hypertrophy in patients with moderate hypertension treated with enalapril, losartan or a combination of the two drugs at lower doses. METHODS: Patients of both sexes with moderate hypertension confirmed by ambulatory monitoring of arte-rial blood pressure and with left ventricular hypertrophy on echocardiogram were assigned to three groups: enalapril (35 mg/day, n=15), losartan (175 mg/day, n=15) and enalapril+losartan (15 mg+100 mg/day, n=16). The patients received the drugs for 10 months. RESULTS: The three therapeutic regimens were equally effective in reducing blood pressure and left ventricular mass index (LVMI, g/m2): 141±3.9 to 123±3.6 in the enalapril group (p
机译：目的：比较依那普利，氯沙坦或小剂量两种药物联合治疗的中度高血压患者左室肥厚的消退。方法：通过动态监测动脉血压和超声心动图检查发现左心室肥厚的中度高血压患者被分为三组：依那普利（35 mg /天，n = 15），氯沙坦（175 mg /天） ，n ＝ 15）和依那普利+氯沙坦（15mg + 100mg /天，n ＝ 16）。患者接受药物治疗10个月。结果：三种治疗方案在依那普利组中均有效降低血压和左心室质量指数（LVMI，g / m2）：141±3.9至123±3.6（p

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