...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Autism & Developmental Language Impairments >Predictors of reliable symptom change: Secondary analysis of the Preschool Autism Communication Trial:
【24h】

Predictors of reliable symptom change: Secondary analysis of the Preschool Autism Communication Trial:

机译：可靠的症状改变的预测因素：幼儿园自闭症传播试验的二次分析：

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Background and aimsDespite recent gains in the amount and quality of early autism intervention research, identifying what works for whom remains an ongoing challenge. Exploiting data from the Preschool Autism Communication Trial (PACT), we undertook secondary analysis to explore prognostic indicators and predictors of response to one year of PACT therapy versus treatment as usual within this large and rigorously characterised cohort recruited across three UK trial sites.MethodsIn this secondary analysis of variability in child gains on the primary trial outcome measure – social-communication symptom severity – we used a pragmatic and data-driven approach to identify a subgroup of children who showed reliable improvement and a subgroup showing clear lack thereof. We then tested which among several baseline child and family factors – including measures routinely collected in research trials and clinical practice – varied as a function of child outcome status and treatment group.ResultsGreater baseline child...
机译：背景和目标尽管早期自闭症干预研究的数量和质量有所提高，但确定对谁有效的方法仍是一个持续的挑战。利用学龄前自闭症交流试验（PACT）中的数据，我们进行了二次分析，以探讨在这三个英国试验地点招募的庞大且严格特征的队列中，对PACT治疗一年与通常治疗相比的预后指标和预测因子。在主要试验结果指标（社交沟通症状的严重程度）上对儿童得益的变异性进行了二次分析，我们使用了一种务实且以数据为依据的方法来识别表现出可靠改善的儿童亚组和明显缺乏这种改善的儿童亚组。然后，我们测试了几个基线儿童和家庭因素中的哪些因素（包括研究试验和临床实践中常规收集的指标）随儿童预后状态和治疗组而变化的结果。更大的基线儿童...

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号