Interaction between the BDNF Val66Met polymorphism and childhood trauma on cortical functional network in non-clinical adults

Yourim Kim; Dongil Min; Yong-Wook Kim; Seung-Hwan Lee

首页> 外文期刊>IBRO Reports >Interaction between the BDNF Val66Met polymorphism and childhood trauma on cortical functional network in non-clinical adults

【24h】

Interaction between the BDNF Val66Met polymorphism and childhood trauma on cortical functional network in non-clinical adults

机译：BDNF Val66Met基因多态性与儿童非临床成人皮层功能网络上的创伤之间的相互作用

获取原文

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

Genetic properties of hub connectivity in the human brain The recent availability of comprehensive brain-wide gene expression atlases provides opportunities to investigate the tran- scriptomic correlates of large-scale neural phenotypes. Our recent work in meso-scale mouse and micro-scale C. elegans connectomes suggests that connected pairs of hubs - network elements with a large number of connections which play a central role in integrated brain function - show increased transcriptional coupling that is, in part, driven by genes regulating oxidative metabolism. To under- stand if these distinctive genetic properties of hub connectivity hold in the human brain we investigated the heritability, transcriptional coupling, and polygenic basis of cortical hub connectivity.

机译：人脑中枢纽连接的遗传特性最近可获得的全脑基因表达图谱为研究大规模神经表型的转录组相关性提供了机会。我们最近在中尺度小鼠和线虫秀丽隐杆线虫的连接组中的研究表明，集线器的连接对-具有大量连接的网络元素，在整合的大脑功能中起着核心作用-显示出增加的转录偶联，部分是，由调节氧化代谢的基因驱动。为了了解轮毂连通性的这些独特遗传特性是否在人脑中起作用，我们研究了皮质轮毂连通性的遗传性，转录偶联和多基因基础。

著录项

来源
《IBRO Reports》 |2019年第1期|共2页
作者
Yourim Kim; Dongil Min; Yong-Wook Kim; Seung-Hwan Lee;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种
中图分类神经病学与精神病学;
关键词

相似文献

外文文献
中文文献
专利

1. Interaction between BDNF Val66Met and childhood trauma on adult's violent suicide attempt. [J] . Perroud N, Courtet P, Vincze I, Genes, brain, and behavior . 2008,第3期

机译：BDNF Val66Met与儿童成人暴力自杀未遂的创伤之间的相互作用。
2. No association between the BDNF Val66Met polymorphism and mood status in a non-clinical community sample of 7389 older adults. [J] . Surtees PG, Wainwright NW, Willis-Owen SA, Journal of psychiatric research . 2007,第5期

机译：在非临床社区样本的7389名成年人中，BDNF Val66Met多态性与情绪状态之间没有关联。
3. Influence on childhood emotional neglect and BDNF Val66Met polymorphism on psychological symptoms and cortical structures [J] . M.J. Jin, S. Jeon, H.N. Seo, International journal of psychophysiology: official journal of the International Organization of Psychophysiology . 2018,第期

机译：对童年情绪疏忽和BDNF Val66met多态性对心理症状和皮质结构的影响
4. Genetics of bipolar disorder: focus on BDNF Val66Met polymorphism [C] . Jinbo Fan, Pamela Skla Symposium on Growth Factors and Psychiatric Disorders . 2008

机译：双相障碍的遗传学：专注于BDNF Val66met多态性
5. The influence of BDNF Val66Met polymorphism on cognition, depression, quality of life, and motor symptoms in individuals with Parkinson's disease after dynamic cycling. [D] . Harper, Sara A. 2016

机译：BDNF Val66Met基因多态性对动态循环后帕金森氏病患者认知，抑郁，生活质量和运动症状的影响。
6. Interaction of Motor Training and Intermittent Theta Burst Stimulation in Modulating Motor Cortical Plasticity: Influence of BDNF Val66Met Polymorphism [O] . Mina Lee, Song E. Kim, Won Sup Kim, 2010

机译：运动训练和间歇性θ爆发刺激在调节运动皮质可塑性中的相互作用：BDNF Val66Met多态性的影响。
7. Interaction between BDNF Val66Met and childhood trauma on adult's violent suicide attempt [O] . Perroud, N., Courtet, P., Vincze, Ilona, 2008

机译：BDNF Val66Met与儿童创伤对成人暴力自杀未遂的相互作用

Interaction between the BDNF Val66Met polymorphism and childhood trauma on cortical functional network in non-clinical adults

摘要

著录项

相似文献

相关主题

期刊订阅