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Ethanol extract of mixture of Astragali Radix and Salviae Miltiorrhizae Radix, alleviates in unpredictable chronic mild stress-induced depression mouse model

机译:黄芪和丹参混合物的乙醇提取物缓解不可预测的慢性轻度应激诱发的抑郁症小鼠模型

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Role of executive functions in statistical learning Statistical learning (SL) is a fundamental neurocognitive mech- anism that enables us to extract complex probabilistic regularities embedded in the environment. However, individual differences in SL have not been comprehensively characterized yet. We hypoth- esized that SL would be influenced differently by individuals’ executive function (EF) and working memory (WM) capacity. The study included two sessions on two separate days. In Session 1, participants performed various neuropsychological tests known to be involved in EF and WM. In Session 2, participants per- formed the Alternating Serial Reaction Time (ASRT) task that has previously shown to capture statistical learning of probabilistic associations. Participants were asked to press one out of the four buttons which corresponded to the target presented on the screen. The ASRT task had three different trial types: pattern trials with high probability condition, random trials with high probability condition (random-high), and random trials with low probabil- ity condition (random-low). The difference between random-high and random-low trials was defined as ‘SL score.’ As random-high and random-low trials were separated solely by probability, we could examine pure SL effects. According to our results, partici- pants showed significant SL both in terms of reaction times and.
机译:执行功能在统计学习中的作用统计学习(SL)是一种基本的神经认知机制,使我们能够提取嵌入在环境中的复杂概率规律。但是,SL的个体差异尚未得到全面表征。我们假设,个体的执行功能(EF)和工作记忆(WM)能力会对SL产生不同的影响。该研究包括分别在两天之内的两次会议。在会议1中,参与者进行了各种已知与EF和WM有关的神经心理学测试。在第2节中,参与者执行了交替序列反应时间(ASRT)任务,该任务先前已显示为捕获概率关联的统计学习。要求参与者按与屏幕上显示的目标相对应的四个按钮中的一个。 ASRT任务具有三种不同的试验类型:具有高概率条件的模式试验,具有高概率条件的随机试验(随机-高)和具有低概率条件的随机试验(随机-低)。随机高位试验和随机低位试验之间的差异定义为“ SL得分”。由于随机高位试验和随机低位试验仅通过概率分开,因此我们可以检验纯净的SL效应。根据我们的结果,参与者在反应时间和反应时间上均显示出显着的SL。

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