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首页> 外文期刊>Annals of Saudi medicine. >Association between breast arterial calcifications found on mammography and coronary artery calcifications in asymptomatic Saudi women
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Association between breast arterial calcifications found on mammography and coronary artery calcifications in asymptomatic Saudi women

机译：乳房X光检查发现的乳房动脉钙化与无症状沙特女性的冠状动脉钙化之间的关联

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BACKGROUND: Currently, there are no data on the prevalence of breast arterial calcification (BAC) in Saudi women. Furthermore, there are no data on the relationship between BAC and coronary artery calcium score (CACS) as a coronary artery disease (CAD) risk factor in Saudi women who undergo mammography. OBJECTIVE: Examine the role of BAC as a potential female-specific risk factor for CAD in Saudi women in order to investigate the relationship between BAC and CACS in women who undergo a screening mammography, and study the relationship between BAC and CAD risk factors, including age, diabetes mellitus, hypertension, chronic kidney disease (CKD), dyslipidemia, and family history of CAD. DESIGN: Retrospective, medical records review. SETTING: Single tertiary care center. PATIENTS AND METHODS: The study cohort included women who had mammograms and a CACS scan, and for whom data on CAD risk stratification and CAD risk factors had been collected within one year of each other from 2014 to 2017. Women with CAD were excluded from the study. MAIN OUTCOME MEASURES: Breast arterial calcification as a marker for coronary artery disease. SAMPLE SIZE: 307 Saudi women. RESULTS: BAC was found in 142 (46%) patients in the study population. BAC+ women were significantly older than the BAC- women ( P =.001), and a strong association was found between BAC and CACS ( P =.0001), diabetes ( P =.0001), hypertension ( P =.021), and CKD ( P =.0031). However, no association was found between BAC and tobacco smoking, dyslipidemia, and family history of CAD. In addition, a strong correlation was found between CACS and the components of the BAC score ( P CONCLUSIONS: The proportion of BAC in Saudi women is 46%, and there may be a strong association between BAC and CAC, age, hypertension, and CKD. A large-scale prospective research study is necessary to validate the role of BAC on screening mammography as a CAD risk stratification tool and before routine reporting of BAC on a mammography report.
机译：背景：目前，尚无关于沙特女性乳房动脉钙化（BAC）患病率的数据。此外，尚无关于在进行乳房X线摄影的沙特女性中BAC与冠状动脉钙化评分（CACS）作为冠状动脉疾病（CAD）危险因素之间关系的数据。目的：检查BAC作为沙特女性CAD中潜在的女性特异性危险因素的作用，以调查接受乳腺钼靶筛查的女性BAC和CACS之间的关系，并研究BAC与CAD危险因素之间的关系，包括年龄，糖尿病，高血压，慢性肾脏病（CKD），血脂异常和CAD家族史。设计：回顾性，病历审查。单位：三级护理中心。患者与方法：该研究队列包括接受乳房X光检查和CACS扫描的女性，从2014年至2017年，彼此之间在一年之内收集了有关CAD危险分层和CAD危险因素的数据。研究。主要观察指标：乳房动脉钙化可作为冠状动脉疾病的标志。样本大小：307名沙特女性。结果：在研究人群中的142名患者中发现了BAC（46％）。 BAC +妇女的年龄明显大于BAC-妇女（P = .001），并且BAC和CACS（P = .0001），糖尿病（P = .0001），高血压（P = .021），和CKD（P = .0031）。但是，在BAC与吸烟，血脂异常和CAD家族史之间没有关联。此外，发现CACS与BAC评分的组成部分之间有很强的相关性（P结论：沙特女性中BAC的比例为46％，BAC与CAC，年龄，高血压和CKD之间可能存在强相关性。必须进行大规模的前瞻性研究研究，以验证BAC在筛查乳腺X线照片中作为CAD风险分层工具的作用，并且需要在BAC在乳腺X线照片上进行常规报告之前。

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