...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Avicenna >Heat in the Arabian Gulf: An analytical review of the impact of ambient temperature on the oral glucose tolerance test
【24h】

Heat in the Arabian Gulf: An analytical review of the impact of ambient temperature on the oral glucose tolerance test

机译：阿拉伯海湾的高温：环境温度对口服葡萄糖耐量试验的影响的分析综述

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Diabetes mellitus (DM) and gestational diabetes (GDM) are often diagnosed and their long-term progression monitored either by a fasting blood glucose test (FGT) or an oral blood glucose tolerance test (OGTT). These tests are well-standardized and are conveniently carried out via blood samples drawn from the patient's arm, which are later analyzed to measure blood glucose concentration. Pre-analytical guidelines for laboratory analysis of blood samples intended for the measurement of plasma glucose maintain that the two principal factors which contribute to poor reproducibility of the OGTT are (i) the variable effects of administration of a hyperosmolar glucose solution on gastric emptying, and (ii) the ambient temperature while the blood sample is being captured. Although viewing ambient temperature as a purely random effect may be acceptable for routine diagnostic tests carried out in “the West”, the substantially higher regular temperatures experienced throughout the year by many African, Asian and Middle-Eastern countries suggest that in some locations and circumstances, ambient temperature might be better regarded as a systematic influence on the OGTT. The principal purpose of this short literature review is to highlight the potentially significant influence of ambient temperature (during the blood-draw) on the results of OGTT blood glucose measurements. Physicians and healthworkers should be aware of this phenomenon which not only can affect the diagnoses for particular patients but is also capable of producing a significant impact on subsequent prevalence estimates for both diabetes and gestational diabetes. Further studies should be conducted throughout the Arabian Gulf to elucidate the magnitude of this effect on local populations by making use of well-characterized patients under standardized conditions where temperature and humidity can be strictly controlled.
机译：通常通过空腹血糖测试（FGT）或口服血糖耐受测试（OGTT）诊断糖尿病（DM）和妊娠糖尿病（GDM），并监测其长期进展。这些测试标准化良好，可方便地通过从患者手臂抽取的血液样本进行，然后进行分析以测量血糖浓度。用于血浆葡萄糖测量的血液样本实验室分析的分析前指南认为，导致OGTT重现性较差的两个主要因素是：（i）高渗葡萄糖溶液对胃排空的影响不同，以及（ii）采集血液样本时的环境温度。尽管将环境温度视为纯粹的随机效应对于“西方国家”进行的常规诊断测试可能是可以接受的，但许多非洲，亚洲和中东国家全年所经历的常规温度明显较高，这表明在某些位置和环境下，最好将环境温度视为对OGTT的系统影响。这篇简短的文献综述的主要目的是强调环境温度（在抽血期间）对OGTT血糖测量结果的潜在重大影响。医师和卫生工作者应意识到这种现象，不仅会影响特定患者的诊断，而且还会对随后的糖尿病和妊娠糖尿病的患病率估计产生重大影响。应该在整个阿拉伯海湾进行进一步的研究，以通过在温度和湿度可以严格控制的标准化条件下，利用特征明确的患者，来阐明对当地人口的影响程度。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号