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首页> 外文期刊>Asian Journal of Scientific Research >Successful Treatment of Canine Parvovirus Infection in Naturally Infected Puppies
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Successful Treatment of Canine Parvovirus Infection in Naturally Infected Puppies

机译：在自然感染的幼犬中成功治疗犬细小病毒感染

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Background and Objective: Canine Parvovirus infection (CPV) causes high moralities among infected puppies, low survival and recovery rate in most of treated cases. So, the aim of this study was to develop a successful method for treatment of CPV infection in dogs with high recovery rate and to evaluate different types of treatment used to treat CPV infection. Materials and Methods: In this study, 360 puppies showing signs suggestive for CPV infection were subjected to clinical examination; Rapid Immunochromatography assay (IC) on fecal samples to detect viral antigen. Treatment of disease was applied using supportive classical treatment for all of the infected puppies while 2 groups (each of 120 puppies) received also Feliserin Plus and Zylexis as trail for treatment using antibodies specific against Feline panleukopenia virus (FPV) as a source for interferon to control viral infection. Results: Clinical examination of diseased puppies revealed the presence of depression, pyrexia, anorexia, thirst, vomiting, diarrhea and dehydration. The IC on fecal samples was positive for CPV in all the 360 examined puppies. Recovery rate in the form of clinical improvement and survival of diseased animals were significantly higher in the group treated by Feliserin Plus (81.7%), followed by the group treated by Zylexis (16.6%). Conclusion: The results of this study exhibited that the use of Feline specific neutralizing antibodies against FPV showed promising results against CPV infection in comparison to the old classical treatment and could be applied for CPV infection in diseased dogs.
机译：背景与目的：犬细小病毒感染（CPV）在大多数受治疗的病例中引起被感染幼犬的高道德，低存活率和恢复率。因此，本研究的目的是开发一种成功治疗高回收率犬CPV感染的方法，并评估用于治疗CPV感染的不同类型的治疗方法。材料和方法：在这项研究中，对360头显示有CPV感染迹象的幼犬进行了临床检查。对粪便样品进行快速免疫色谱分析（IC），以检测病毒抗原。使用支持性经典疗法对所有感染的幼犬进行疾病治疗，而2组（每组120只幼犬）也接受Feliserin Plus和Zylexis作为治疗方案，使用针对猫泛白细胞减少症病毒（FPV）的特异性抗体作为干扰素的来源控制病毒感染。结果：患病幼犬的临床检查发现存在抑郁，发热，厌食，口渴，呕吐，腹泻和脱水。粪便样品上的IC在所有360只受检幼犬中均为CPV阳性。用Feliserin Plus治疗的组（81.7％），其次是用Zylexis治疗的组（16.6％），其临床改善和患病动物存活率的恢复率显着更高。结论：这项研究的结果表明，与传统的传统疗法相比，使用抗FPV的猫特异性中和抗体显示出了对CPV感染的有希望的结果，可用于患病犬的CPV感染。

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