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首页> 外文期刊>Indian Journal of Community Medicine >Magnitude of Gestational Diabetes Mellitus, its Influencing Factors and Diagnostic Accuracy of Capillary Blood Testing for its Detection at a Tertiary Care Centre, Rajkot, Gujarat
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Magnitude of Gestational Diabetes Mellitus, its Influencing Factors and Diagnostic Accuracy of Capillary Blood Testing for its Detection at a Tertiary Care Centre, Rajkot, Gujarat

机译：妊娠糖尿病的数量，影响因素以及在古吉拉特邦拉杰科特市三级护理中心检测毛细血管血液化验的诊断准确性

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Background: Gestational diabetes mellitus (GDM) occurs during pregnancy which affects mother, fetus, and outcome of pregnancy, hence early detection is necessary. The objective of this study was to ascertain the validity of glucometer over standard biochemical testing for detection of GDM and to estimate prevalence of GDM and its associated risk factors. Materials and Methods: A hospital-based study was conducted at Antenatal clinics of Obstetrics Department, tertiary care hospital, based on the “National Guidelines for Diagnosis and Management of GDM.” Totally 357 pregnant women between 21 and 28 weeks of gestational age agreed were included in the study from January to March 2016. After obtaining written consent, one step procedure was offered to pregnant women by giving 75 g of anhydrous glucose dissolving in 200–250 ml of water. After 2 h, glucose level was estimated by capillary testing with glucometer and venous glucose by glucose oxidase test. Results: GDM was found in 20.4% pregnant women with capillary testing done by glucometer compare to 11.5% with venous blood testing. GDM was found higher among literates, homemakers, Hindus, people living in nuclear family, belongs to middle class, residing in urban area, primigravidae, obese and with gestational age between 21 and 24 weeks. Intermediate agreement (Kappa = 0.42) was found between two methods with sensitivity of 70.7%, specificity of 86.1%, positive predictive value 39.7%, and negative predictive value 95.8%. Conclusion: Intermediate agreement between two methods indicates glucometer testing can be used to screen pregnant women at an early gestational age (21 weeks), at the community level by health-care workers.
机译：背景：妊娠期糖尿病（GDM）会在妊娠期间发生，影响母亲，胎儿和妊娠结局，因此有必要及早发现。这项研究的目的是确定血糖仪相对于用于检测GDM的标准生化测试的有效性，并估计GDM的患病率及其相关的危险因素。资料和方法：根据“ GDM诊断和管理的国家指南”，在三级护理医院产科的产前诊所进行了一项基于医院的研究。从2016年1月至2016年3月，共有357名同意在21至28周胎龄的孕妇进入研究。在获得书面同意后，通过将75 g无水葡萄糖溶解在200–250 ml中为孕妇提供了一步步骤水。 2小时后，通过用血糖仪的毛细管测试估计葡萄糖水平，并通过葡萄糖氧化酶测试估计静脉葡萄糖。结果：在20.4％的孕妇中，通过血糖仪进行的毛细血管测试发现了GDM，而在静脉血液测试中发现的GDM为11.5％。在识字者，家庭主妇，印度教徒，生活在有核家庭的人中，属于中产阶级，居住在城市地区，初产妇，肥胖且胎龄在21至24周之间的人群中发现GDM较高。两种方法之间存在中间一致性（Kappa = 0.42），敏感性为70.7％，特异性为86.1％，阳性预测值为39.7％，阴性预测值为95.8％。结论：两种方法之间的中间协议表明，血糖仪测试可用于在社区一级由医护人员筛查妊娠早期（21周）的孕妇。

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